晚发性癫痫与中风:诊断、发病机制和预防

IF 2.7 3区 医学 Q2 CLINICAL NEUROLOGY
Hermann Stefan , Georg Michelson
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引用次数: 0

摘要

脑卒中与迟发性癫痫(LOE)的关联讨论,特别关注其诊断,发病机制和预防。除了流行病学数据,包括来自不同年龄组的数据外,还审查了急性症状性和远端症状性癫痫发作的发生机制。考虑与癫痫发作和卒中后癫痫(PSE)相关的危险因素,以及该研究的方法学局限性。在未来的研究中,应该对中风发作前7天或7天后的急性和远程症状性癫痫发作进行区分,因为不同的急性症状性癫痫发作(ASSs)本身可能导致不同的PSE风险。迄今为止,爱情的年龄定义是不一致的。比较成人寿命时期,很明显中风和癫痫发作表现出相似的患病率概况。青年期、老年期和老年期可能与LOE亚型的年龄、血管合并症和其他特征的区分有关。提出了一种可能有助于脑血管预防的阶梯计划策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Late onset epilepsy and stroke: Diagnosis, pathogenesis and prevention
The association of stroke and late-onset epilepsy (LOE) is discussed with special regard to its diagnosis, pathogenesis, and prevention. In addition to epidemiological data, including those from different age groups, the mechanisms for the development of acute symptomatic and remote symptomatic seizures are reviewed. The risk factors associated with seizures and post-stroke epilepsy (PSE) are considered, along with the methodological limitations of the study. For future research, the distinction between acute and remote symptomatic seizure before or after seven days from stroke onset should be reviewed because different acute symptomatic seizures (ASSs) themselves can entail a variable PSE risk. The definition of LOE by age is hitherto inconsistent. Comparing adult lifespan epochs, it is evident that stroke and seizures exhibit similar prevalence profiles. Young adulthood, old adulthood, and elderly epochs may be relevant for the differentiation of LOE subtype by age, vascular comorbidity, and other characteristics. A step-scheme strategy as a possible contribution to cerebrovascular prevention approaches is proposed.
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来源期刊
Seizure-European Journal of Epilepsy
Seizure-European Journal of Epilepsy 医学-临床神经学
CiteScore
5.60
自引率
6.70%
发文量
231
审稿时长
34 days
期刊介绍: Seizure - European Journal of Epilepsy is an international journal owned by Epilepsy Action (the largest member led epilepsy organisation in the UK). It provides a forum for papers on all topics related to epilepsy and seizure disorders.
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