茄科药用植物次生代谢物合成的转录组分析

IF 2.2 4区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE
P.H.S. Dasanya, M. Hewadikaram
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引用次数: 0

摘要

导言植物产生的次生代谢物在植物适应环境中的各种生物和非生物压力方面发挥着至关重要的作用。植物次生代谢物在制药和其他草药相关产业中具有重要价值。因此,植物次生代谢物的分离和表征近年来受到了特别关注。在异源生物的植物次生代谢物代谢工程中,需要阐明次生代谢物的生物合成途径。方法数据来自各种在线电子资源,包括 PubMed、Google Scholar 和 Scopus 等。使用茄科植物、次生代谢物、转录组学、药用植物和 RNA 测序等关键词制定搜索策略,共搜索了约 111 篇研究和综述文章。结果对茄科药用植物从头转录组学研究的成果进行了广泛阐释,主要集中在候选基因的鉴定、通路分析差异基因表达分析、分子标记物的发现以及转录因子的鉴定等方面。讨论对茄科药用植物从头转录组学研究的主要意义进行了讨论,同时也指出了需要注意的重大局限性。此外,还讨论了从头转录组研究的近期和未来趋势,以期鼓励在茄科药用植物中开展更多的从头转录组研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Transcriptomic Analysis of Secondary Metabolite Biosynthesis in Solanaceae Medicinal Plants

Transcriptomic Analysis of Secondary Metabolite Biosynthesis in Solanaceae Medicinal Plants

Introduction

Secondary metabolites produced in plants play a vital role in their adaptation to various biotic and abiotic stresses in the environment. Plant secondary metabolites possess significant value in the pharmaceutical and other herbal medicine-related industries. Therefore, the isolation and characterisation of plant secondary metabolites have gained a special interest in recent years. The elucidation of secondary metabolite biosynthetic pathways is required in the metabolic engineering of plant secondary metabolites in heterologous organisms.

Methods

Data were retrieved from various online electronic resources, including PubMed, Google Scholar, and Scopus, among others. Keywords such as Solanaceae plants, secondary metabolites, transcriptomic, medicinal plants, and RNA sequencing were used to formulate search strategies across approximately 111 research and review articles.

Results

The outcomes of the de novo transcriptomic studies performed in Solanaceae medicinal plants have been extensively elucidated with a primary focus on the identification of candidate genes, pathway analysis differential gene expression analysis, the discovery of molecular markers, and the identification of transcription factors.

Discussion

The primary significance of de novo transcriptomic studies performed in Solanaceae medicinal plants has been discussed with significant limitations necessitating attention. Moreover, recent and future trends of de novo transcriptomic studies have been addressed with the intention of encouraging more de novo transcriptomic studies in Solanaceae medicinal plants.

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来源期刊
Journal of Herbal Medicine
Journal of Herbal Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
3.90
自引率
0.00%
发文量
94
期刊介绍: The Journal of Herbal Medicine, the official journal of the National Institute of Medical Herbalists, is a peer reviewed journal which aims to serve its readers as an authoritative resource on the profession and practice of herbal medicine. The content areas of the journal reflect the interests of Medical Herbalists and other health professionals interested in the clinical and professional application of botanical medicines. The objective is to strengthen the research and educational base of herbal medicine with research papers in the form of case studies, original research articles and reviews, monographs, clinical trials and relevant in vitro studies. It also publishes policy statements, opinion pieces, book reviews, conference proceedings and profession related information such as pharmacovigilance reports providing an information source for not only the Herbal Practitioner but any Health professional with an interest in phytotherapy.
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