A. Tarnovska, A. Heneha, D. Hrytchyshyn, Ya. Muzyka, V. Chemiorkina, N. Fedkovych
{"title":"不同年龄段正常和有病变男性精子图的定量和定性指标","authors":"A. Tarnovska, A. Heneha, D. Hrytchyshyn, Ya. Muzyka, V. Chemiorkina, N. Fedkovych","doi":"10.30970/vlubs.2024.91.10","DOIUrl":null,"url":null,"abstract":"The indicators of spermograms of men of different ages: younger (20-29 years), middle (30-39 years) and older age groups (40-50 years) with normozoospermia, oligoteratoasthenozoospermia, teratoasthenozoospermia and hypoteratozoospermia were studied. Spermograms were obtained during examination of patients at the “Alternative Clinic” reproductive medicine clinic. Spermograms were evaluated according to the following indicators: volume of ejaculate, viscosity, number of spermatozoa in 1 ml of ejaculate; the total number of sperm in the ejaculate; motility of spermatozoa according to movement categories A and B; sperm morphology (percentage of morphologically normal and morphologically altered spermatozoa), Farris fertility index and number of active spermatozoa. Having analyzed the results of spermograms of men of different age groups, we found out that the main indicators of deviations in these spermograms are the mobility of spermatozoa according to movement categories A and B; sperm morphology (percentage of morphologically normal and morphologically altered spermatozoa), Farris fertility index and number of active spermatozoa. In order to quantitatively assess the influence of oligoteratoasthenozoospermia, teratoasthenozoospermia and hypoteratozoospermia and the age factor on the general variability of spermogram indicators of men of the younger (20–29 years), middle (30–39 years) and older (40–50 years) age groups, we conducted 41 series of univariate and 18 series of two-factor analysis of variance. After conducting a anova analysis, we established that the share of the influence of the studied diseases in the overall variability of the sperm motility index by category B in men of the younger age group is insignificant and amounts to 10 % of the total contribution, instead, the share of the influence of unaccounted factors is increasing, which is 90 % of the total contribution - this may indicate the presence of pathological processes in the reproductive organs of men. The share of the influence of the age factor on the overall variability of such indicators of spermograms as motility of spermatozoa according to category A and B, morphology of spermatozoa (percentage of morphologically normal and degenerate spermatozoa), Farris fertility index and activity and viability of spermatozoa of younger, middle and older age groups is insignificant and is in ranging from 1 to 6 %.","PeriodicalId":173155,"journal":{"name":"Visnyk of Lviv University. 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Spermograms were evaluated according to the following indicators: volume of ejaculate, viscosity, number of spermatozoa in 1 ml of ejaculate; the total number of sperm in the ejaculate; motility of spermatozoa according to movement categories A and B; sperm morphology (percentage of morphologically normal and morphologically altered spermatozoa), Farris fertility index and number of active spermatozoa. Having analyzed the results of spermograms of men of different age groups, we found out that the main indicators of deviations in these spermograms are the mobility of spermatozoa according to movement categories A and B; sperm morphology (percentage of morphologically normal and morphologically altered spermatozoa), Farris fertility index and number of active spermatozoa. In order to quantitatively assess the influence of oligoteratoasthenozoospermia, teratoasthenozoospermia and hypoteratozoospermia and the age factor on the general variability of spermogram indicators of men of the younger (20–29 years), middle (30–39 years) and older (40–50 years) age groups, we conducted 41 series of univariate and 18 series of two-factor analysis of variance. After conducting a anova analysis, we established that the share of the influence of the studied diseases in the overall variability of the sperm motility index by category B in men of the younger age group is insignificant and amounts to 10 % of the total contribution, instead, the share of the influence of unaccounted factors is increasing, which is 90 % of the total contribution - this may indicate the presence of pathological processes in the reproductive organs of men. 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引用次数: 0
摘要
研究了不同年龄段男性的精子图指标:年轻(20-29 岁)、中年(30-39 岁)和老年(40-50 岁)正常无精子症、少精子症、无精子症和精子质量低下。精子图是在 "替代诊所 "生殖医学诊所对患者进行检查时获得的。精子图根据以下指标进行评估:射精量、粘度、1 毫升射精中的精子数量;射精中的精子总数;根据运动类别 A 和 B 确定的精子运动能力;精子形态(形态正常和形态改变精子的百分比)、法里斯生育指数和活动精子数量。在对不同年龄组男性的精子图结果进行分析后,我们发现这些精子图中的主要偏差指标包括:精子移动性(按照移动类别 A 和 B)、精子形态(形态正常和形态改变的精子百分比)、法里斯生育指数和活动精子数量。为了定量评估少精子症、无精子症、少精子症和年龄因素对青年组(20-29 岁)、中年组(30-39 岁)和老年组(40-50 岁)男性精子图指标总体变异性的影响,我们进行了 41 次单因素方差分析和 18 次双因素方差分析。在进行 anova 分析后,我们确定所研究的疾病对 B 类年轻男性精子活力指数总体变化的影响份额微不足道,仅占总贡献的 10%,相反,未考虑因素的影响份额在增加,占总贡献的 90%--这可能表明男性生殖器官存在病理过程。年龄因素对精子图指标总体变异性的影响比例微乎其微,如 A 类和 B 类精子的运动性、精子形态(形态正常和退化精子的百分比)、法里斯生育指数以及年轻、中年和老年组精子的活动力和存活率,在 1%至 6%之间。
Quantitative and qualitative indicators of spermograms of men of different age groups in normal and with pathologies
The indicators of spermograms of men of different ages: younger (20-29 years), middle (30-39 years) and older age groups (40-50 years) with normozoospermia, oligoteratoasthenozoospermia, teratoasthenozoospermia and hypoteratozoospermia were studied. Spermograms were obtained during examination of patients at the “Alternative Clinic” reproductive medicine clinic. Spermograms were evaluated according to the following indicators: volume of ejaculate, viscosity, number of spermatozoa in 1 ml of ejaculate; the total number of sperm in the ejaculate; motility of spermatozoa according to movement categories A and B; sperm morphology (percentage of morphologically normal and morphologically altered spermatozoa), Farris fertility index and number of active spermatozoa. Having analyzed the results of spermograms of men of different age groups, we found out that the main indicators of deviations in these spermograms are the mobility of spermatozoa according to movement categories A and B; sperm morphology (percentage of morphologically normal and morphologically altered spermatozoa), Farris fertility index and number of active spermatozoa. In order to quantitatively assess the influence of oligoteratoasthenozoospermia, teratoasthenozoospermia and hypoteratozoospermia and the age factor on the general variability of spermogram indicators of men of the younger (20–29 years), middle (30–39 years) and older (40–50 years) age groups, we conducted 41 series of univariate and 18 series of two-factor analysis of variance. After conducting a anova analysis, we established that the share of the influence of the studied diseases in the overall variability of the sperm motility index by category B in men of the younger age group is insignificant and amounts to 10 % of the total contribution, instead, the share of the influence of unaccounted factors is increasing, which is 90 % of the total contribution - this may indicate the presence of pathological processes in the reproductive organs of men. The share of the influence of the age factor on the overall variability of such indicators of spermograms as motility of spermatozoa according to category A and B, morphology of spermatozoa (percentage of morphologically normal and degenerate spermatozoa), Farris fertility index and activity and viability of spermatozoa of younger, middle and older age groups is insignificant and is in ranging from 1 to 6 %.