儿童惊厥性癫痫的病因和结果

Q3 Medicine
A. Wasim, Shihab S Al Maawali, Abdulrahman S AlJabri, F. Al Amrani, Faraz Ahmad, Ahmed Mansi, Amna Al Futaisi
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引用次数: 0

摘要

研究目的本研究旨在评估儿童惊厥性癫痫状态(CSE)的病因、管理和预后,并强调影响患者预后的因素。研究方法在一项跨度为 2020 年至 2023 年的回顾性研究中,对苏丹卡布斯大学医院急诊科(ED)、重症监护室(HD)和重症监护室(ICU)收治的 93 名惊厥性癫痫(CSE)患儿进行了分析。出院时的改良Rankin量表决定了CSE的预后。研究结果研究对象为 93 名儿童(平均年龄为 4.84 岁 ± 3.64 岁),主要为阿曼人(92.47%)。急性14症状(37.7%)和发热状态(31.2%)是主要原因。67.44%的 15 例患者使用地西泮作为一线治疗,发作持续时间中位数为 45 分钟。16 76.34% 的患者在 60 分钟内成功控制病情。55.9%的患者恢复到基线水平,5.38%的患者死亡,38.7%的患者致残。病因和持续时间对疗效有显著影响(P < 0.05)。结论急性无症状是 CSE 最常见的病因,持续时间越长,死亡率和神经系统残疾率越高。因此,及时、适当地治疗 CSE 至关重要。此外,识别和治疗潜在病因对于缩短 CSE 的持续时间和改善预后至关重要。关键词病因 结局 惊厥性癫痫修正Rankin量表
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aetiology and Outcome of Childhood Convulsive Status Epilepticus
Objective: This study aimed to evaluate the etiology, management, and outcomes of convulsive status epilepticus (CSE) in children highlighting the factors that affect patient outcome. Methods: In a retrospective study spanning 2020 to 2023, 93 children with convulsive status epilepticus (CSE) treated at Sultan Qaboos University Hospital's emergency department (ED), High Dependency (HD), and intensive care unit (ICU) were analyzed. The Modified Rankin Scale at discharge determined CSE outcome. Results: Study of 93 children (mean age 4.84 years ± 3.64), predominantly Omani (92.47%). Acute 14 symptomatic (37.7%) and  febrile tatus (31.2%) were primary causes. Diazepam used in 67.44% 15 cases as first-line treatment, with median seizure duration of 45 minutes. Successful control achieved in 16 76.34% within 60 minutes. Return to baseline in 55.9%, 5.38% mortality, and 38.7% disability. Etiology and 17 duration significantly impacted outcomes (p < 0.05). Conclusion: Acute symptomatic is the most common etiology of CSE, and a longer duration is associated with higher mortality and neurological disability. Therefore, managing CSE promptly and appropriately is crucial. Furthermore, identifying and treating the underlying cause is essential to reduce the duration of CSE and improve the outcome. Keywords: Etiology, Outcome, Convulsive Status Epilepticus, Modified Rankin Scale
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来源期刊
CiteScore
2.00
自引率
0.00%
发文量
86
审稿时长
7 weeks
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