使用薰衣草油和迷迭香油评估和配制抗微生物凝胶

Sunil Gupta
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摘要

简介迷迭香是一种非常重要的传统药草,可用于治疗多种疾病。由于具有多种生物活性化合物,迷迭香属植物被认为是许多医学体系中最重要的属植物之一。本次分析对该植物的生物活性化合物进行了化学研究。材料和方法:使用 Clevenger 仪器,借助蒸馏法提取迷迭香精油。结果对抗菌凝胶的外观和均匀性、粗糙度、pH 值、粘度、粒度等进行了评估。抗微生物凝胶呈白色,涂抹时感觉光滑,有芳香气味。将草药凝胶的抗菌活性与标准进行比较后发现,草药凝胶的抗菌活性较低。结论从结果中可以推断出,抗微生物凝胶具有良好的外观、均质性和易涂抹性。抗微生物凝胶是用 carbopol 934 等胶凝剂和聚乙二醇配制而成的,并对配方进行了各种参数评估。三种配方的 pH 值都在皮肤 pH 值范围内。与标准凝胶相比,抗菌凝胶的效果较差,因为它们的主要成分是迷迭香油和薰衣草油,而迷迭香油和薰衣草油具有抗微生物特性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation and Formulation of Anti-Microbial Gel Using Lavender Oil and Rosemary Oil
Introduction: Salvia Rosemary is a medicinal herb of great importance for traditional applications against several kinds of disease. Because of the range of bioactive compounds, the genus of Salvia Rosemary is regarded as one of the most significant genus utilised in many medical systems. This plant was chemically investigated for its bioactive compounds in the current analysis. Materials and Methods: The essential oil of Rosemary extract by using clevenger apparatus with the help of distillation method. Result: The anti-microbial gel was evaluated for appearance and homogeneity, grittiness, pH, viscosity, particle size etc. The anti-microbial gel was white in colour which feels smooth on application and have aromatic odour. The antimicrobial activity of herbal gel was compared with standard and it’s found to be less effective. Conclusion: It was inferred from the result that anti-microbial gel was good in appearance, homogeniety and easily spreadable. The anti-microbial gel was prepared using gelling agent like carbopol 934 along with polyethylene glycol and the formulation were subjected to various evaluation parameters. The pH of all three formulations were in the range of the pH of the skin. The Antimicrobial gel was less effective then standard gel as they have rosemary oil and lavender oil as their key ingredients because of their anti-microbial property.
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