30 年后的 BRCA1 和朋友们

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2024-06-17 DOI:10.1038/s41576-024-00754-6

William D. Foulkes

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引用次数: 0

摘要

事后看来，对癌症易感基因 BRCA1 的认识及其后来的克隆是乳腺癌和卵巢癌遗传学的决定性时刻，值得庆贺。在发现和克隆癌症易感基因 BRCA1 三十年后，William Foulkes 回顾了乳腺癌和卵巢癌遗传学的这一决定性时刻，以及该领域所取得的成就。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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BRCA1 and friends 30 years on

With the benefit of hindsight, recognition of the cancer susceptibility gene BRCA1 and its later cloning were defining moments for breast and ovarian cancer genetics that should be celebrated. Thirty years after the discovery and cloning of the cancer susceptibility gene BRCA1, William Foulkes reflects on this defining moment for breast and ovarian cancer genetics and how far the field has come.

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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