Anan S. Jarab , Razan Z. Mansour , Suhaib Muflih , Walid Al-Qerem , Shrouq R. Abu Heshmeh , Tareq Mukattash , Yazid N. Al Hamarneh , Maher Khdour
{"title":"心肌梗死门诊患者不遵医嘱用药的情况：一项基于医院的研究","authors":"Anan S. Jarab , Razan Z. Mansour , Suhaib Muflih , Walid Al-Qerem , Shrouq R. Abu Heshmeh , Tareq Mukattash , Yazid N. Al Hamarneh , Maher Khdour","doi":"10.1016/j.cegh.2024.101682","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Despite the availability of effective medications for the treatment of myocardial infarction (MI), treatment outcomes are suboptimal due to medication non-adherence. The aim of this study was to assess medication adherence and its associated factors among patients with MI.</p></div><div><h3>Methods</h3><p>This cross-sectional study was conducted on outpatients with MI in the cardiology clinic at a major hospital in Jordan. Medication adherence was assessed using the validated Arabic version of the 4-item Medication Adherence Scale. Ordinal regression was conducted to identify the variables associated with medication non-adherence.</p></div><div><h3>Results</h3><p>A total of 333 patients participated in the study. The median age was 58 years (57–60). Medication non-adherence was expressed by 54.6 % of the participants. Having less than college/university education (Coefficient = −0.625, 95%Cl (−1.191 to −0.06), P = 0.03) and increased medication-related concerns (Coefficient = −0.065, 95 % Cl (−0.126 to −0.003), P = 0.04) were associated with decreased medication adherence. Other factors, including having no family history of cardiovascular disease (CVD) (Coefficient = 0.757, 95%Cl (0.218–1.295), P = 0.006) and increased medication necessity (Coefficient = 0.186, 95%Cl (0.133–0.239), P < 0.001) were associated with high medication adherence.</p></div><div><h3>Conclusion</h3><p>The current study demonstrated a high rate of medication non-adherence in MI patients, necessitating the need to develop tailored pharmaceutical care interventions that address patients' medication-related beliefs, focusing on their perceptions of medication necessity and concerns, particularly in patients with low education level and those with a positive family history of CVD.</p></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213398424001787/pdfft?md5=c4922a37d781d20774ca7ec6c815e4b2&pid=1-s2.0-S2213398424001787-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Medication non-adherence among outpatients with myocardial infarction: A hospital-based study\",\"authors\":\"Anan S. Jarab , Razan Z. Mansour , Suhaib Muflih , Walid Al-Qerem , Shrouq R. Abu Heshmeh , Tareq Mukattash , Yazid N. Al Hamarneh , Maher Khdour\",\"doi\":\"10.1016/j.cegh.2024.101682\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Despite the availability of effective medications for the treatment of myocardial infarction (MI), treatment outcomes are suboptimal due to medication non-adherence. The aim of this study was to assess medication adherence and its associated factors among patients with MI.</p></div><div><h3>Methods</h3><p>This cross-sectional study was conducted on outpatients with MI in the cardiology clinic at a major hospital in Jordan. Medication adherence was assessed using the validated Arabic version of the 4-item Medication Adherence Scale. Ordinal regression was conducted to identify the variables associated with medication non-adherence.</p></div><div><h3>Results</h3><p>A total of 333 patients participated in the study. The median age was 58 years (57–60). Medication non-adherence was expressed by 54.6 % of the participants. Having less than college/university education (Coefficient = −0.625, 95%Cl (−1.191 to −0.06), P = 0.03) and increased medication-related concerns (Coefficient = −0.065, 95 % Cl (−0.126 to −0.003), P = 0.04) were associated with decreased medication adherence. Other factors, including having no family history of cardiovascular disease (CVD) (Coefficient = 0.757, 95%Cl (0.218–1.295), P = 0.006) and increased medication necessity (Coefficient = 0.186, 95%Cl (0.133–0.239), P < 0.001) were associated with high medication adherence.</p></div><div><h3>Conclusion</h3><p>The current study demonstrated a high rate of medication non-adherence in MI patients, necessitating the need to develop tailored pharmaceutical care interventions that address patients' medication-related beliefs, focusing on their perceptions of medication necessity and concerns, particularly in patients with low education level and those with a positive family history of CVD.</p></div>\",\"PeriodicalId\":46404,\"journal\":{\"name\":\"Clinical Epidemiology and Global Health\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-06-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2213398424001787/pdfft?md5=c4922a37d781d20774ca7ec6c815e4b2&pid=1-s2.0-S2213398424001787-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Epidemiology and Global Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2213398424001787\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Epidemiology and Global Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213398424001787","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Medication non-adherence among outpatients with myocardial infarction: A hospital-based study
Background
Despite the availability of effective medications for the treatment of myocardial infarction (MI), treatment outcomes are suboptimal due to medication non-adherence. The aim of this study was to assess medication adherence and its associated factors among patients with MI.
Methods
This cross-sectional study was conducted on outpatients with MI in the cardiology clinic at a major hospital in Jordan. Medication adherence was assessed using the validated Arabic version of the 4-item Medication Adherence Scale. Ordinal regression was conducted to identify the variables associated with medication non-adherence.
Results
A total of 333 patients participated in the study. The median age was 58 years (57–60). Medication non-adherence was expressed by 54.6 % of the participants. Having less than college/university education (Coefficient = −0.625, 95%Cl (−1.191 to −0.06), P = 0.03) and increased medication-related concerns (Coefficient = −0.065, 95 % Cl (−0.126 to −0.003), P = 0.04) were associated with decreased medication adherence. Other factors, including having no family history of cardiovascular disease (CVD) (Coefficient = 0.757, 95%Cl (0.218–1.295), P = 0.006) and increased medication necessity (Coefficient = 0.186, 95%Cl (0.133–0.239), P < 0.001) were associated with high medication adherence.
Conclusion
The current study demonstrated a high rate of medication non-adherence in MI patients, necessitating the need to develop tailored pharmaceutical care interventions that address patients' medication-related beliefs, focusing on their perceptions of medication necessity and concerns, particularly in patients with low education level and those with a positive family history of CVD.
期刊介绍：
Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
