肾移植中体内尿路结石干预的当前视角:系统回顾。

IF 2.1 3区 医学 Q2 UROLOGY & NEPHROLOGY
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引用次数: 0

摘要

目的对文献进行系统性回顾(SR),以评估有关体内外结石手术的成功率和并发症的现有证据:符合纳入条件的研究侧重于调查肾结石供体体内外结石手术的成功率和并发症。根据 "系统综述和元分析首选报告项目 "指南进行了SR检索。检索包括 Web of Science、PubMed 和 Scopus 数据库,仅纳入英文文章。结果:在筛选了 1726 篇摘要后,本研究共纳入了 16 项研究,共计 209 名患者。结石的平均大小为 5.6 毫米,大多数肾脏含有单发结石,位于下肾萼。体内外结石手术后,平均无石率为 95.4%。体外手术的平均时间为17.3分钟。关于术中并发症,有两名患者(1%)在气压碎石过程中出现粘膜损伤。至于术后并发症,两名患者(1%)出现了血管并发症。在泌尿系统并发症方面,24 名患者(11.5%)出现血尿,1 名患者(0.5%)肾盂出现血凝块。随访期间,7 名患者(3.3%)出现尿路感染,3 名患者(1.4%)出现尿路结石。此外,一名患者(0.5%)的输尿管膀胱造口完全闭塞,需要进行翻修:鉴于当前技术和工艺的进步,体内腔外结石手术越来越被认为是肾结石供体的一种有效而安全的选择:本研究中生成和/或分析的数据集可向相应作者索取。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current Perspectives on Endourological Ex Vivo Stone Interventions in Kidney Transplantation: A Systematic Review

Objective

To conduct a systematic review (SR) of literature to assess the existing evidence concerning the success and complications of endourological ex vivo stone surgeries.

Methods

Eligible studies for inclusion focused on investigating the success and/or complications related to endourological ex vivo surgeries in donors with nephrolithiasis. A SR was undertaken in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search included databases of Web of Science, PubMed, and Scopus and only article in English were included. Studies published between 2002 and 2023 included in this SR.

Results

After screening 1726 abstracts, this SR included 16 studies with a total of 209 patients. The mean stone size was 5.6 mm and majority of kidneys contained single stones, located in the lower calyx. After ex vivo endourological stone surgeries, the average stone-free rate was found to be 95.4%. The mean duration of ex vivo surgery was 17.3 minutes. Regarding intraoperative complications, two patients (1%) experienced mucosal injuries during pneumatic lithotripsy. As for postoperative complications, two patients (1%) experienced vascular complications. In terms of urological complications, hematuria was observed in 24 patients (11.5%), while one patient (0.5%) experienced clot formation in renal pelvis. Seven patients (3.3%) had urinary tract infections, and three patients (1.4%) developed urolithiasis during the follow-up. Additionally, one patient (0.5%) experienced complete occlusion of ureteroneocystostomy and required revision.

Conclusion

Given the advancements in current technology and techniques, endourological ex vivo stone surgeries are increasingly recognized as an effective and safe option for donors with nephrolithiasis.

Trial registration

This systematic review was registered under the protocol registration number CRD42024538384/PROSPERO.

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来源期刊
Urology
Urology 医学-泌尿学与肾脏学
CiteScore
3.30
自引率
9.50%
发文量
716
审稿时长
59 days
期刊介绍: Urology is a monthly, peer–reviewed journal primarily for urologists, residents, interns, nephrologists, and other specialists interested in urology The mission of Urology®, the "Gold Journal," is to provide practical, timely, and relevant clinical and basic science information to physicians and researchers practicing the art of urology worldwide. Urology® publishes original articles relating to adult and pediatric clinical urology as well as to clinical and basic science research. Topics in Urology® include pediatrics, surgical oncology, radiology, pathology, erectile dysfunction, infertility, incontinence, transplantation, endourology, andrology, female urology, reconstructive surgery, and medical oncology, as well as relevant basic science issues. Special features include rapid communication of important timely issues, surgeon''s workshops, interesting case reports, surgical techniques, clinical and basic science review articles, guest editorials, letters to the editor, book reviews, and historical articles in urology.
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