Tas1R3依赖和独立识别尿道中的糖类以及簇细胞在此过程中的作用（生物学进展 6/2024）

IF 3.2 3区生物学 Q3 MATERIALS SCIENCE, BIOMATERIALS

Advanced biology Pub Date : 2024-06-14 DOI:10.1002/adbi.202470061

Patricia Schmidt, Alexander Perniss, Martin Bodenbenner-Tuerich, Silke Wiegand, Loic Briand, Klaus Deckmann

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引用次数: 0

摘要

尿路感染糖浓度升高显示出感染的危险因素。克劳斯-德克曼（Klaus Deckmann）及其合作者撰写的编号为 2400117 的文章阐明了尿道中的糖监测。尿道丛细胞（UTC）是监测尿道腔和启动保护机制的哨兵。监测通过两条途径进行。一种是依赖UTC/Tas1R3的途径，另一种是独立于Tas1R3的途径，在UTC和其他尿道上皮细胞中均可发现。糖类会增加UTC/Tas1R3 依赖性的逼尿肌活动。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Tas1R3 Dependent and Independent Recognition of Sugars in the Urethra and the Role of Tuft Cells in this Process (Adv. Biology 6/2024)

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Tas1R3 Dependent and Independent Recognition of Sugars in the Urethra and the Role of Tuft Cells in this Process (Adv. Biology 6/2024)

Urinary Tract Infection

Increased sugar concentrations display risk factors for infections. Article number 2400117 by Klaus Deckmann and co-workers clarifies sugar monitoring in the urethra. Urethral tuft cells (UTC) are sentinels monitoring the urethral lumen and initiating protective mechanisms. Monitoring occurs via two pathways. A UTC/Tas1R3 dependent and a Tas1R3 independent pathway, found in both UTC and in other urethral epithelial cells. Sugars increases detrusor muscle activity UTC/Tas1R3 dependently.

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来源期刊

Advanced biology Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

6.60

自引率

0.00%

发文量

130