Sara E Childs-Sanford, Wendy K Kiso, Dennis L Schmitt
{"title":"在低纬度地区管理的亚洲象（大象）的血清维生素 d 和选定的钙稳态生物标志物。","authors":"Sara E Childs-Sanford, Wendy K Kiso, Dennis L Schmitt","doi":"10.1638/2023-0082","DOIUrl":null,"url":null,"abstract":"<p><p>An understanding of species-specific vitamin D metabolism and its role in calcium homeostasis is essential for correct diet formulation and development of husbandry protocols for managed nondomestic species. This study documented serum vitamin D metabolites and other analytes involved in calcium homeostasis in Asian elephants (<i>Elephas maximus</i>) managed at a latitude similar to their wild natural habitat. Serum values for 33 elephants managed at a low latitude were measured in the peak of summer, revealing low vitamin D<sub>2</sub> (25(OH)D<sub>2</sub> 2.3 ± 0.6 ng/ ml and 24,25(OH)<sub>2</sub>D<sub>2</sub> 2.17 ± 0.52 ng/ml) and nondetectable vitamin D<sub>3</sub>. Serum minerals (calcium, phosphorus, magnesium), ionized calcium, and parathyroid hormone were within normal reported ranges. In comparison with previously reported values in elephants managed at a high latitude, 25(OH)D<sub>2</sub> (<i>P</i> < 0.001), 24,25(OH)<sub>2</sub>D<sub>2</sub> (<i>P</i> = 0.001), and magnesium (<i>P</i> = 0.013) were significantly lower, and parathyroid hormone was significantly higher (<i>P</i> < 0.001). The lack of D<sub>3</sub> production during ample sun exposure at a low latitude suggests that Asian elephants are incapable of cutaneous photobiosynthesis of vitamin D, and that low serum D<sub>2</sub> is normal for this species.</p>","PeriodicalId":17667,"journal":{"name":"Journal of Zoo and Wildlife Medicine","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"SERUM VITAMIN D AND SELECTED BIOMARKERS OF CALCIUM HOMEOSTASIS IN ASIAN ELEPHANTS (<i>ELEPHAS MAXIMUS</i>) MANAGED AT A LOW LATITUDE.\",\"authors\":\"Sara E Childs-Sanford, Wendy K Kiso, Dennis L Schmitt\",\"doi\":\"10.1638/2023-0082\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>An understanding of species-specific vitamin D metabolism and its role in calcium homeostasis is essential for correct diet formulation and development of husbandry protocols for managed nondomestic species. This study documented serum vitamin D metabolites and other analytes involved in calcium homeostasis in Asian elephants (<i>Elephas maximus</i>) managed at a latitude similar to their wild natural habitat. Serum values for 33 elephants managed at a low latitude were measured in the peak of summer, revealing low vitamin D<sub>2</sub> (25(OH)D<sub>2</sub> 2.3 ± 0.6 ng/ ml and 24,25(OH)<sub>2</sub>D<sub>2</sub> 2.17 ± 0.52 ng/ml) and nondetectable vitamin D<sub>3</sub>. Serum minerals (calcium, phosphorus, magnesium), ionized calcium, and parathyroid hormone were within normal reported ranges. In comparison with previously reported values in elephants managed at a high latitude, 25(OH)D<sub>2</sub> (<i>P</i> < 0.001), 24,25(OH)<sub>2</sub>D<sub>2</sub> (<i>P</i> = 0.001), and magnesium (<i>P</i> = 0.013) were significantly lower, and parathyroid hormone was significantly higher (<i>P</i> < 0.001). The lack of D<sub>3</sub> production during ample sun exposure at a low latitude suggests that Asian elephants are incapable of cutaneous photobiosynthesis of vitamin D, and that low serum D<sub>2</sub> is normal for this species.</p>\",\"PeriodicalId\":17667,\"journal\":{\"name\":\"Journal of Zoo and Wildlife Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2024-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Zoo and Wildlife Medicine\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1638/2023-0082\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Zoo and Wildlife Medicine","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1638/2023-0082","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
SERUM VITAMIN D AND SELECTED BIOMARKERS OF CALCIUM HOMEOSTASIS IN ASIAN ELEPHANTS (ELEPHAS MAXIMUS) MANAGED AT A LOW LATITUDE.
An understanding of species-specific vitamin D metabolism and its role in calcium homeostasis is essential for correct diet formulation and development of husbandry protocols for managed nondomestic species. This study documented serum vitamin D metabolites and other analytes involved in calcium homeostasis in Asian elephants (Elephas maximus) managed at a latitude similar to their wild natural habitat. Serum values for 33 elephants managed at a low latitude were measured in the peak of summer, revealing low vitamin D2 (25(OH)D2 2.3 ± 0.6 ng/ ml and 24,25(OH)2D2 2.17 ± 0.52 ng/ml) and nondetectable vitamin D3. Serum minerals (calcium, phosphorus, magnesium), ionized calcium, and parathyroid hormone were within normal reported ranges. In comparison with previously reported values in elephants managed at a high latitude, 25(OH)D2 (P < 0.001), 24,25(OH)2D2 (P = 0.001), and magnesium (P = 0.013) were significantly lower, and parathyroid hormone was significantly higher (P < 0.001). The lack of D3 production during ample sun exposure at a low latitude suggests that Asian elephants are incapable of cutaneous photobiosynthesis of vitamin D, and that low serum D2 is normal for this species.
期刊介绍：
The Journal of Zoo and Wildlife Medicine (JZWM) is considered one of the major sources of information on the biology and veterinary aspects in the field. It stems from the founding premise of AAZV to share zoo animal medicine experiences. The Journal evolved from the long history of members producing case reports and the increased publication of free-ranging wildlife papers.
The Journal accepts manuscripts of original research findings, case reports in the field of veterinary medicine dealing with captive and free-ranging wild animals, brief communications regarding clinical or research observations that may warrant publication. It also publishes and encourages submission of relevant editorials, reviews, special reports, clinical challenges, abstracts of selected articles and book reviews. The Journal is published quarterly, is peer reviewed, is indexed by the major abstracting services, and is international in scope and distribution.
Areas of interest include clinical medicine, surgery, anatomy, radiology, physiology, reproduction, nutrition, parasitology, microbiology, immunology, pathology (including infectious diseases and clinical pathology), toxicology, pharmacology, and epidemiology.
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