尿道混合腺癌和小细胞神经内分泌癌伴广泛转移和化疗耐药：病例报告。

IF 2.4 3区医学 Q2 PATHOLOGY

Diagnostic Pathology Pub Date : 2024-06-14 DOI:10.1186/s13000-024-01490-5

Sarah Obiedat, Khaled Murshed, Lajos Szabados, Khaled Al Rumaihi, Issam Al Bozom

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引用次数: 0

摘要

尿道神经内分泌癌极为罕见。我们描述了一例 33 岁男性患者的病例，他出现血尿并被诊断为尿道腺癌和小细胞神经内分泌癌的复合瘤。患者发病时还伴有广泛转移，因此转诊接受化疗。然而，尽管进行了治疗，病情还是出现了进展。尿道肿瘤中的神经内分泌癌成分虽然罕见，但却非常重要，因为这种组织学类型预后较差，临床结果具有侵袭性。

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Urachal mixed adenocarcinoma and small cell neuroendocrine carcinoma with widespread metastasis and resistance to chemotherapy: a case report.

Neuroendocrine carcinoma arising from the urachus is extremely rare. We describe a case of a 33-year-old gentleman who presented with hematuria and diagnosed to have a composite adenocarcinoma and small cell neuroendocrine carcinoma arising from the urachus. The patient also had widespread metastasis at the time of presentation, therefore, he was referred for chemotherapy. However, the disease showed progression despite treatment. Recognition of neuroendocrine carcinoma component in urachal tumors, although rare, is very essential as this histologic type carries poor prognosis with aggressive clinical outcome.

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来源期刊

Diagnostic Pathology 医学-病理学

CiteScore

4.60

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： Diagnostic Pathology is an open access, peer-reviewed, online journal that considers research in surgical and clinical pathology, immunology, and biology, with a special focus on cutting-edge approaches in diagnostic pathology and tissue-based therapy. The journal covers all aspects of surgical pathology, including classic diagnostic pathology, prognosis-related diagnosis (tumor stages, prognosis markers, such as MIB-percentage, hormone receptors, etc.), and therapy-related findings. The journal also focuses on the technological aspects of pathology, including molecular biology techniques, morphometry aspects (stereology, DNA analysis, syntactic structure analysis), communication aspects (telecommunication, virtual microscopy, virtual pathology institutions, etc.), and electronic education and quality assurance (for example interactive publication, on-line references with automated updating, etc.).