酒精使用障碍量表测试在确定接受抗逆转录病毒治疗者是否患有酒精使用障碍方面的实用性。

IF 1.2 4区 医学 Q4 HEALTH POLICY & SERVICES
Ashraf Kagee, Wylene Saal, Adelle Sterley
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引用次数: 0

摘要

我们试图确定酒精使用障碍鉴定测试(AUDIT)在筛查 688 名抗逆转录病毒疗法(ART)使用者中酒精使用障碍(AUD)的实用性。我们使用受试者操作特征曲线(ROC)分析来评估 AUDIT 与 DSM 结构化临床访谈(SCID)相比是否能可靠地检测出 AUD。在样本中,22.09%(CI:19.05% 至 25.38%)的参与者符合 AUD 的诊断标准。在男性(n = 135)和女性(n = 553)中,患病率估计值分别为 31.9% 和 19.7%。对于男性,6 分临界值预测 AUD 的灵敏度为 88.36%(95%CI:74.92-96.11),特异度为 88.04%(95%CI:79.61-93.88)。对于女性而言,AUDIT 临界值为 4 分的最佳灵敏度为 92.66%(95%CI:86.05%-96.78%),特异度为 93.24%(95%CI:90.49%-95.40%)。对于男性,AUDIT 的阳性预测值 (PPV) 为 75.55%(95% CI:66.26%-85.87%),阴性预测值 (NPV) 为 91.49%(95% CI:87.63%-97.37%);对于女性,PPV 和 NPV 分别为 77.09%(70.34%-82.68%)和 98.11%(96.37%-99.02%)。该工具良好的灵敏度和特异性表明,它可能有助于筛查和转诊可能患有 AUD 的抗逆转录病毒疗法使用者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Utility of the Alcohol Use Disorder Inventory Test in determining caseness for alcohol use disorder among persons receiving antiretroviral therapy.

We sought to determine the utility of the Alcohol Use Disorder Identification Test (AUDIT) in screening for alcohol use disorder (AUD) among 688 users of antiretroviral therapy (ART). We used the receiver operating characteristic (ROC) curve analysis to assess whether the AUDIT reliably detected AUD against the Structured Clinical Interview for the DSM (SCID). Of the samples, 22.09% (CI: 19.05% to 25.38%) of participants met the diagnostic criteria for AUD. Among men (n = 135) and women (n = 553), the prevalence estimates were 31.9% and 19.7%, respectively. For men, a cut-off score of 6 predicted AUD with 88.36% (95%CI: 74.92-96.11) sensitivity and 88.04% (95%CI: 79.61-93.88) specificity. For women, a cut-off score of 4 on the AUDIT yielded an optimal sensitivity of 92.66% (95% CI: 86.05%-96.78%) and a specificity of 93.24% (95% CI: 90.49-95.40%). For men, the AUDIT yielded a positive predictive value (PPV) of 75.55% (95% CI: 66.26%-85.87%) and a negative predictive value (NPV) of 91.49% (95% CI: 87.63-97.37%); for women the PPV and NPV were 77.09% (70.34%-82.68%) and 98.11% (96.37%-99.02%), respectively. The instrument's good sensitivity and specificity indicate it is likely to be useful for screening and referral of ART users who are probably cases of AUD.

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CiteScore
3.50
自引率
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发文量
172
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