{"title":"内源性阿片类药物及其受体的基础科学。","authors":"Simona Tache, Patrick L Kerr, Cristian Sirbu","doi":"10.1007/978-3-031-45493-6_2","DOIUrl":null,"url":null,"abstract":"<p><p>The function of endogenous opioids spans from initiating behaviors that are critical for survival, to responding to rapidly changing environmental conditions. A network of interconnected systems throughout the body characterizes the endogenous opioid system (EOS). EOS receptors for beta-endorphin, enkephalin, dynorphin, and endomorphin underpin the diverse functions of the EOS across biological systems. This chapter presents a succinct yet comprehensive summary of the structure of the EOS, EOS receptors, and their relationship to other biological systems.</p>","PeriodicalId":7360,"journal":{"name":"Advances in neurobiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Foundational Science of Endogenous Opioids and Their Receptors.\",\"authors\":\"Simona Tache, Patrick L Kerr, Cristian Sirbu\",\"doi\":\"10.1007/978-3-031-45493-6_2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The function of endogenous opioids spans from initiating behaviors that are critical for survival, to responding to rapidly changing environmental conditions. A network of interconnected systems throughout the body characterizes the endogenous opioid system (EOS). EOS receptors for beta-endorphin, enkephalin, dynorphin, and endomorphin underpin the diverse functions of the EOS across biological systems. This chapter presents a succinct yet comprehensive summary of the structure of the EOS, EOS receptors, and their relationship to other biological systems.</p>\",\"PeriodicalId\":7360,\"journal\":{\"name\":\"Advances in neurobiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in neurobiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/978-3-031-45493-6_2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Neuroscience\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in neurobiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/978-3-031-45493-6_2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Neuroscience","Score":null,"Total":0}
引用次数: 0
摘要
内源性阿片类药物的功能包括启动对生存至关重要的行为，以及对快速变化的环境条件做出反应。内源性阿片类物质系统（EOS）是一个遍布全身的相互关联的系统网络。内源性阿片系统受体包括β-内啡肽、脑啡肽、达因啡肽和内吗啡肽，这些受体支撑着内源性阿片系统在各个生物系统中发挥不同的功能。本章简明而全面地概述了 EOS 的结构、EOS 受体及其与其他生物系统的关系。
The Foundational Science of Endogenous Opioids and Their Receptors.
The function of endogenous opioids spans from initiating behaviors that are critical for survival, to responding to rapidly changing environmental conditions. A network of interconnected systems throughout the body characterizes the endogenous opioid system (EOS). EOS receptors for beta-endorphin, enkephalin, dynorphin, and endomorphin underpin the diverse functions of the EOS across biological systems. This chapter presents a succinct yet comprehensive summary of the structure of the EOS, EOS receptors, and their relationship to other biological systems.
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