高频重复经颅磁刺激及其对慢性精神分裂症患者症状、认知和主观体验的影响：一项假对照研究。

IF 1 4区医学 Q4 CLINICAL NEUROLOGY

Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2024-06-04 eCollection Date: 2024-01-01 DOI:10.29399/npa.28423

Lijun Liu, Lida Shi, Dongmei Xu, Xuan Wang, Yuhong Wang, Qian Wang, Xinfu Wang

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引用次数: 0

摘要

导言：我们的目的是研究高频重复经颅磁刺激（rTMS）对慢性精神分裂症患者的症状、认知功能和主观体验的影响，并加深对 TMS 方法的全面了解：研究纳入了 33 名慢性精神分裂症患者。17名患者接受了经颅磁刺激，16名患者接受了假性经颅磁刺激。研究人员对所有患者进行了阳性和阴性综合征量表、神经心理状态评估重复性电池量表、洞察力和治疗态度问卷调查，以及由研究人员开发的用于评估经颅磁刺激后体验的自我体验清单：两组患者在症状、认知功能和洞察力方面没有统计学差异。结论：经颅磁刺激治疗并未改善症状、认知功能和洞察力，但提供了更好的自我体验，这可能会提高治疗依从性。

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High-Frequency Repetitive Transcranial Magnetic Stimulation and Its Effects on Symptoms, Cognition and Subjective Experiences in Chronic Schizophrenia: A Sham-Controlled Study.

Introduction: Our object is to examine the effects of high-frequency repetitive transcranial magnetic stimulation (rTMS) on the symptoms, cognitive functions and subjective experiences in patients with chronic schizophrenia and to enhance the overall understanding of the TMS method.

Methods: Thirty three patients who had chronic schizophrenia were included in the study. Seventeen patients received rTMS and 16 received sham. The Positive and Negative Syndrome Scale, Repeatable Battery for the Assessment of Neuropsychological Status Scale, Insight and Treatment Attitudes Questionnaire and a self-experience checklist developed by the researchers to evaluate post-TMS experiences were applied to all patients.

Results: There were no statistical differences between the groups with regard to symptoms, cognitive functions and insight. However rTMS group reported overall better treatment experience and more positive subjective experiences.

Conclusion: rTMS treatment did not cause any improvement in symptoms, cognitive functions and insight but provided a better self-experience, which might improve treatment compliance.

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来源期刊

Noropsikiyatri Arsivi-Archives of Neuropsychiatry CLINICAL NEUROLOGY-

CiteScore

1.70

自引率

9.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Archives of Neuropsychiatry (Arch Neuropsychiatry) is the official journal of the Turkish Neuropsychiatric Society. It is published quarterly, and four editions annually constitute a volume. Archives of Neuropsychiatry is a peer reviewed scientific journal that publishes articles on psychiatry, neurology, and behavioural sciences. Both clinical and basic science contributions are welcomed. Submissions that address topics in the interface of neurology and psychiatry are encouraged. The content covers original research articles, reviews, letters to the editor, and case reports.