用于生物传感器的荧光碳点和石墨烯量子点的最新进展:溶液方法的合成及其医学应用》。

IF 2.6 4区 化学 Q2 BIOCHEMICAL RESEARCH METHODS
Journal of Fluorescence Pub Date : 2025-05-01 Epub Date: 2024-06-13 DOI:10.1007/s10895-024-03809-3
Rafaqat Khan, Amina Qureshi, Muhammad Azhar, Zia Ul Hassan, Sagheer Gul, Saeed Ahmad
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引用次数: 0

摘要

在健康和生物学领域,荧光纳米材料已成为生物传感器应用中极具潜力和非常有用的候选材料。这些典型的功能强大的纳米材料包括碳点(CD)和石墨烯量子点(GQD)以及许多其他金属纳米材料。在医学生物传感器方面,这篇综述文章研究了这些纳米材料的合成技术、多种用途、面临的障碍以及未来的潜力。我们介绍了荧光纳米材料的意义、在医疗领域的应用,以及 CD 和 GQDs 的几种合成技术,包括超声法、水热法、电化学法、表面改性法和溶热法。此外,我们还讨论了它们在生物医学方面的应用,包括生物大分子检测、疾病诊断,并探讨了开发超亮、超灵敏、选择性生物传感器的障碍和前景。这些碳点和石墨烯量子点可用于医疗领域,包括检测生物材料、检测癌症、病毒和 DNA 变异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Recent Progress of Fluorescent Carbon Dots and Graphene Quantum Dots for Biosensors: Synthesis of Solution Methods and their Medical Applications.

Recent Progress of Fluorescent Carbon Dots and Graphene Quantum Dots for Biosensors: Synthesis of Solution Methods and their Medical Applications.

In the fields of health and biology, fluorescent nanomaterials have emerged as highly potential and very useful candidates for use in biosensor applications. These typical highly powerful nanomaterials are carbon dots (CDs) and graphene quantum dots (GQDs) among many other metallic nanomaterials. In the context of medical biosensors, this review article investigates the techniques of synthesis, and many uses of these nanomaterials, the obstacles that they face, and the potential for their future. We cover the significance of fluorescent nanomaterials, their use in the medical field, as well as the several techniques of synthesis for CDs and GQDs, including ultrasonication, hydrothermal, electrochemical method, surface modification, and solvothermal. In addition, we also discuss their biomedical applications, which include biomolecule detection, disease diagnosis and examine the obstacles and prospective possibilities for development of ultra-bright, ultra-sensitive, and selective biosensors for use in in-vivo research.Fluorescent carbon dots and graphene quantum dots is synthesized by using several types of raw material and methods. These Carbon dots and graphene quantum dots are used in the medical field includes detection of biomaterials, detection of cancer, virus and mutation in DNA.

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来源期刊
Journal of Fluorescence
Journal of Fluorescence 化学-分析化学
CiteScore
4.60
自引率
7.40%
发文量
203
审稿时长
5.4 months
期刊介绍: Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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