关于 0.5% 聚维酮碘鼻腔喷雾剂（Nasodine）的碘吸收、安全性和耐受性的第一阶段研究。

IF 7.2 2区医学 Q1 OTORHINOLARYNGOLOGY

International Forum of Allergy & Rhinology Pub Date : 2024-06-13 DOI:10.1002/alr.23389

Peter L. Friedland MBBCh, MMED, FCS, FRACS, Thomas M. Polasek BSc, BPharm (Hons), MD, PhD, FCP, Duncan Topliss MD, FRACP, FACE

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引用次数: 0

摘要

要点PVP-I 是一种广泛使用的杀菌剂，但最近才被提议用于鼻内。现有 PVP-I 鼻用产品的碘吸收程度尚不清楚。使用 Nasodine（0.5% PVP-I 鼻用喷雾剂）吸收碘的临床意义不大。

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Phase 1 study of the iodine absorption, safety, and tolerability of a 0.5% povidone-iodine nasal spray (Nasodine)

Key points

PVP-I is a widely used antiseptic but only recently proposed for intranasal use.
The extent of iodine absorption from available PVP-I nasal products is unknown.
Iodine absorption from use of Nasodine (0.5% PVP-I nasal spray) is not clinically significant.

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来源期刊

International Forum of Allergy & Rhinology OTORHINOLARYNGOLOGY-

CiteScore

11.70

自引率

10.90%

发文量

185

审稿时长

6-12 weeks

期刊介绍： International Forum of Allergy & Rhinologyis a peer-reviewed scientific journal, and the Official Journal of the American Rhinologic Society and the American Academy of Otolaryngic Allergy. International Forum of Allergy Rhinology provides a forum for clinical researchers, basic scientists, clinicians, and others to publish original research and explore controversies in the medical and surgical treatment of patients with otolaryngic allergy, rhinologic, and skull base conditions. The application of current research to the management of otolaryngic allergy, rhinologic, and skull base diseases and the need for further investigation will be highlighted.