限制进食时间与限制每日热量对肥胖男性和女性性激素的影响。

IF 3.6 3区医学 Q2 NUTRITION & DIETETICS

European Journal of Clinical Nutrition Pub Date : 2024-06-12 DOI:10.1038/s41430-024-01461-5

Shuhao Lin, Sofia Cienfuegos, Mark Ezpeleta, Vasiliki Pavlou, Mary-Claire Runchey, Krista A. Varady

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引用次数: 0

摘要

本研究探讨了限时进食（TRE）与每日热量限制（CR）对男性和女性性激素的影响。患有肥胖症的成年人（n = 90）被随机分为 3 组，每组 1 人，为期 12 个月：8小时TRE组（只在中午12:00至晚上8:00进食，不计算卡路里）；CR组（每天限制25%的能量）；或对照组。体重下降（P

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Effect of time restricted eating versus daily calorie restriction on sex hormones in males and females with obesity

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Effect of time restricted eating versus daily calorie restriction on sex hormones in males and females with obesity

This study examined the effects of time restricted eating (TRE) on sex hormones in males and females, versus daily calorie restriction (CR). Adults with obesity (n = 90) were randomized to 1 of 3 groups for 12-months: 8-h TRE (eating only between 12:00 to 8:00 pm, with no calorie counting); CR (25% energy restriction daily); or control. Body weight decreased (P < 0.01) in the TRE and CR groups, relative to controls, in males, premenopausal females, and postmenopausal females, by month 12. Total testosterone, dehydroepiandrosterone (DHEA), and sex hormone binding globulin (SHBG) levels did not change over time, or between groups, in males, premenopausal females, and postmenopausal females. Estradiol, estrone, and progesterone were only measured in postmenopausal females, and remained unchanged. These findings suggest that TRE produces significant weight loss but does not impact circulating sex hormone levels in males and females with obesity over 12 months, relative to CR and controls.

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来源期刊

European Journal of Clinical Nutrition 医学-营养学

CiteScore

10.60

自引率

2.10%

发文量

189

审稿时长

3-6 weeks

期刊介绍： The European Journal of Clinical Nutrition (EJCN) is an international, peer-reviewed journal covering all aspects of human and clinical nutrition. The journal welcomes original research, reviews, case reports and brief communications based on clinical, metabolic and epidemiological studies that describe methodologies, mechanisms, associations and benefits of nutritional interventions for clinical disease and health promotion. Topics of interest include but are not limited to: Nutrition and Health (including climate and ecological aspects) Metabolism & Metabolomics Genomics and personalized strategies in nutrition Nutrition during the early life cycle Health issues and nutrition in the elderly Phenotyping in clinical nutrition Nutrition in acute and chronic diseases The double burden of ''malnutrition'': Under-nutrition and Obesity Prevention of Non Communicable Diseases (NCD)