这与运气有什么关系?研究死亡年龄随机性作用的生成模型,及其对生物考古学的影响。

IF 1.6 4区 医学 Q1 ANTHROPOLOGY
Bronwyn Wyatt, Amy Anderson, Stacey Ward, Laura A. B. Wilson
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引用次数: 0

摘要

导言:运气 "在决定个体暴露于健康损害中的作用是形成死亡样本中死亡年龄分布过程的一个重要组成部分,但很难用传统的骨骼材料生物考古学分析方法来解决这个问题。本研究介绍了一种计算机模拟方法,用于模拟随机性对模拟人群死亡时间表的影响:方法:本研究采用基于代理的模型,对 120 年间的 15100 人进行了研究,以检验出生时的虚弱程度在不同的健康损害可能性下对死亡年龄的预测价值:结果:在考虑到不同的暴露可能性的情况下,出生时的虚弱程度占观察到的个体死亡年龄变化的 18.7%。按暴露可能性进行的分层分析表明,在不同暴露可能性情况下观察到的变异中,仅出生时体弱就可解释10.2%-12.1%的变异,而与暴露于健康损害(即健康损害的严重程度)和死亡可能性相关的随机性则驱动了观察到的大部分变异:结论:应激源暴露的随机性和应激源的内在严重性在该模拟中被低估,但却是死亡率的强大驱动因素。这项研究证明了模拟建模在生物考古学研究中的潜在价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

What's luck got to do with it? A generative model for examining the role of stochasticity in age-at-death, with implications for bioarchaeology

What's luck got to do with it? A generative model for examining the role of stochasticity in age-at-death, with implications for bioarchaeology

Introduction

The role of “luck” in determining individual exposure to health insults is a critical component of the processes that shape age-at-death distributions in mortality samples but is difficult to address using traditional bioarcheological analysis of skeletal materials. The present study introduces a computer simulation approach to modeling stochasticity's contribution to the mortality schedule of a simulated cohort.

Methods

The present study employs an agent-based model of 15,100 individuals across a 120 year period to examine the predictive value of birth frailty on age-at-death when varying the likelihood of exposure to health insults.

Results

Birth frailty, when accounting for varying exposure likelihood scenarios, was found to account for 18.7% of the observed variation in individual age-at-death. Analysis stratified by exposure likelihood demonstrated that birth frailty alone explains 10.2%–12.1% of the variation observed across exposure likelihood scenarios, with the stochasticity associated with exposure to health insults (i.e., severity of health insult) and mortality likelihood driving the majority of variation observed.

Conclusions

Stochasticity of stressor exposure and intrinsic stressor severity are underappreciated but powerful drivers of mortality in this simulation. This study demonstrates the potential value of simulation modeling for bioarchaeological research.

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来源期刊
CiteScore
4.80
自引率
13.80%
发文量
124
审稿时长
4-8 weeks
期刊介绍: The American Journal of Human Biology is the Official Journal of the Human Biology Association. The American Journal of Human Biology is a bimonthly, peer-reviewed, internationally circulated journal that publishes reports of original research, theoretical articles and timely reviews, and brief communications in the interdisciplinary field of human biology. As the official journal of the Human Biology Association, the Journal also publishes abstracts of research presented at its annual scientific meeting and book reviews relevant to the field. The Journal seeks scholarly manuscripts that address all aspects of human biology, health, and disease, particularly those that stress comparative, developmental, ecological, or evolutionary perspectives. The transdisciplinary areas covered in the Journal include, but are not limited to, epidemiology, genetic variation, population biology and demography, physiology, anatomy, nutrition, growth and aging, physical performance, physical activity and fitness, ecology, and evolution, along with their interactions. The Journal publishes basic, applied, and methodologically oriented research from all areas, including measurement, analytical techniques and strategies, and computer applications in human biology. Like many other biologically oriented disciplines, the field of human biology has undergone considerable growth and diversification in recent years, and the expansion of the aims and scope of the Journal is a reflection of this growth and membership diversification. The Journal is committed to prompt review, and priority publication is given to manuscripts with novel or timely findings, and to manuscripts of unusual interest.
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