母亲在怀孕期间接触致喘职业与儿童未来患哮喘的风险:荟萃分析。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Parmida Seraj Ebrahimi, Matineh Ardestani Bala, Zahra Mashhadi Tafreshi, Hana Piroti, Mehrsa Mostafaei, Bita Ghahremani, Faezeh Shaverdi, Alireza Imani Porshokouh, Niloofar Deravi, Mohadeseh Poudineh, Minoo Roostaie
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引用次数: 0

摘要

母亲在妊娠期间的职业暴露与其子女日后罹患哮喘之间的关系一直是一个争论不休的问题,而有关这一问题的队列研究结果也一直存在争议。目前的研究是首次系统性回顾和荟萃分析,旨在评估妊娠期母体职业暴露对儿童日后罹患哮喘的风险。为了检索符合条件的研究,我们在 2023 年 8 月 10 日前在以下数据库中进行了高级文献检索:PubMed、Scopus 和 Google Scholars。对相关文章的标题和摘要进行了筛选,并对全文进行了审阅。进行了数据提取;因此,对纳入的文章进行了分析,以评估提及的关联性。从总共 10 项队列研究和 5372 条记录中发现,孕期职业暴露于致喘物与日后儿童哮喘之间没有显著关系。母体在怀孕期间接触致哮喘职业的患者患哮喘儿童的汇总几率比为 1.03(95% 置信区间,0.97-1.09),I2= 13% p=0.62。结论是,母体职业暴露与儿童未来的哮喘之间没有明显的关联。不过,还需要未来的大规模研究来支持这些结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Maternal occupational exposure to asthmogenic during pregnancy and the future risk of asthma in children: A meta-analysis.

The association between maternal occupational exposure during pregnancy and the subsequent development of asthma in their children has always been a matter of debate, and the results of cohort studies on this issue have been controversial. The current study is the first systematic review and meta-analysis aimed at evaluating the risk of developing subsequent asthma in children based on maternal occupational exposure during the gestation period. To retrieve eligible studies, an advanced literature search was performed up to August 10, 2023 from the following databases: PubMed, Scopus, and Google Scholars. The title and abstract of related articles were screened; hence, the full texts were reviewed. Data extraction was conducted; hence, the included articles were analyzed to assess the mention association. From a total of 10 cohort studies with a total record of 5372, it was found that there is no significant relationship between occupational exposure to asthmogenic during pregnancy and later asthma in children. The pooled odds ratio of asthmatic children in patients with maternal occupational exposure to asthmogenic during pregnancy was 1.03 (95% confidence interval, 0.97-1.09) I2= 13% p=0.62. It was concluded that there is no significant association between maternal occupational exposure and future asthma in children. However, future large-scale studies are required to support these results.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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