踏步行走会损害早期青光眼患者和老年对照组患者的视觉功能。

IF 2.4 3区 医学 Q2 OPHTHALMOLOGY
Rosalie Beyer, Khaldoon O Al-Nosairy, Constantin Freitag, Francie H Stolle, Martin Behrens, Gokulraj T Prabhakaran, Hagen Thieme, Lutz Schega, Michael B Hoffmann
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引用次数: 0

摘要

目的:视力受损是老年人跌倒的额外风险因素。我们研究了跑步机(TM)行走对健康老人和因青光眼导致的早期中度视功能障碍老人的视觉功能的影响这一假设:30 名 64-83 岁的健康对照组(HC)和 18 名 62-82 岁的青光眼患者(GLA)参加了这项横断面研究。TM行走对视觉功能的影响通过双眼进行评估:(i) 有和无拥挤效应的最佳矫正视力(BCVA);(ii) 对比敏感度(CS);(iii) 视野(平均偏差,VF-MD)。在两种速度条件下,即(i)以自己喜欢的速度快速行走和(ii)以每小时 3.5 公里的固定速度行走时,对参与者站立或 TM 步行时的视觉功能进行了测试:大多数早期中度 VF 缺失的 GLA 与 HC 的表现相同。与 GROUP 无关,SPEED 对视觉功能的影响在统计学上是显而易见的,在以下方面具有较大的统计学效应大小:(i) BCVA 的两种类型,平均损失为 0.02-0.05 logMAR (η2 = 0.41);(ii) VF-MD 的平均损失为 1 dB (η2 = 0.70),但对 CS 没有影响:在此,我们介绍了一种评估行走时视觉功能的范例。我们提供的概念证明,我们的方法可以识别步行引起的视觉功能损失,即两组人在 TM 步行过程中 BCVA 和 VF 灵敏度的下降。因此,该方法有望用于研究视力损伤与活动能力的关系,最终研究晚期青光眼患者跌倒频率增加的原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Treadmill-walking impairs visual function in early glaucoma and elderly controls.

Treadmill-walking impairs visual function in early glaucoma and elderly controls.

Aims: Impaired vision is an additional risk factor in elderly for falls. We investigated the hypothesis that treadmill (TM) walking affects visual function in both healthy elderly and those with early-moderate visual dysfunction due to glaucoma.

Methods: Thirty healthy controls (HC) aged 64-83 years and 18 glaucoma patients (GLA) aged 62-82 years participated in this cross-sectional study. The impact of TM-walking on visual function was assessed binocularly for (i) best-corrected visual acuity (BCVA) with and without crowding effect, (ii) contrast sensitivity (CS), and (iii) and visual field (mean deviation, VF-MD). Visual function was tested while participants were standing or during TM-walking for 2 speed conditions: (i) fast walking at their preferred speed and (ii) walking at a fixed speed of 3.5 km/h.

Results: GLA, most with early-moderate VF loss, performed equally well as HC. Independent of GROUP, an impact of SPEED on visual functions was statistically evident with large statistical effect size for (i) both types of BCVA with a mean loss of 0.02-0.05 logMAR (η2 = 0.41) and (ii) VF-MD with mean loss of 1 dB (η2 = 0.70), but not for CS.

Conclusions: Here, we introduce a paradigm for the assessment of visual function during walking. We provide proof-of-concept that our approach allows for the identification of walking induced visual function loss, i.e., a deterioration of BCVA and VF-sensitivity during TM-walking in both groups. It is therefore of promise for the investigation of the relation of vision impairment and mobility, ultimately the increased frequency of falls in advanced glaucoma.

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来源期刊
CiteScore
5.40
自引率
7.40%
发文量
398
审稿时长
3 months
期刊介绍: Graefe''s Archive for Clinical and Experimental Ophthalmology is a distinguished international journal that presents original clinical reports and clini-cally relevant experimental studies. Founded in 1854 by Albrecht von Graefe to serve as a source of useful clinical information and a stimulus for discussion, the journal has published articles by leading ophthalmologists and vision research scientists for more than a century. With peer review by an international Editorial Board and prompt English-language publication, Graefe''s Archive provides rapid dissemination of clinical and clinically related experimental information.
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