Helena Levyn MD, Tejas Subramanian BE, Alana Eagan MPH, Nora Katabi MD, Johanna Goldberg MSLIS, Daniel W. Scholfield MChB, MRCS, Giovanna L. Caxeiro MD, Richard J. Wong MD, Marc A. Cohen MD, Jatin P. Shah MD, PhD, DSc, FRCS (Hon), Snehal G. Patel MD, Ian Ganly MD
{"title":"腮腺切除术治疗深叶多形性腺瘤的并发症和复发率较高。","authors":"Helena Levyn MD, Tejas Subramanian BE, Alana Eagan MPH, Nora Katabi MD, Johanna Goldberg MSLIS, Daniel W. Scholfield MChB, MRCS, Giovanna L. Caxeiro MD, Richard J. Wong MD, Marc A. Cohen MD, Jatin P. Shah MD, PhD, DSc, FRCS (Hon), Snehal G. Patel MD, Ian Ganly MD","doi":"10.1002/hed.27840","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Pleomorphic adenoma (PA) is a common parotid tumor, yet due to the relative rarity of deep lobe PA (DLPA), there is a paucity of information about its clinical presentation and surgical outcomes.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>We reviewed the charts of patients with previously untreated parotid PA between the years 1990 and 2015. Clinical parameters and surgical outcomes were compared between superficial lobe PA (SLPA) and DLPA.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The cohort comprised 147 cases of DLPA and 222 cases of SLPA. DLPA were larger (median 2.6 cm vs. 2.0 cm, <i>p</i> < 0.001), more often discovered incidentally on imaging (33%, <i>n</i> = 48) and had unique presentations (pharyngeal mass, dysphagia, otalgia). Postsurgical complications were more frequently observed in DLPA (41% vs. 30% in SLPA, <i>p</i> = 0.025), mainly transient facial nerve weakness. DLPA also showed higher recurrence rates (<i>n</i> = 6, 4.1% vs. <i>n</i> = 1, 0.4%, <i>p</i> = 0.016).</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Parotidectomy for DLPA carries a higher risk of complications and recurrence compared to SLPA.</p>\n </section>\n </div>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Parotidectomy for deep lobe pleomorphic adenomas is associated with higher rates of complications and recurrence\",\"authors\":\"Helena Levyn MD, Tejas Subramanian BE, Alana Eagan MPH, Nora Katabi MD, Johanna Goldberg MSLIS, Daniel W. Scholfield MChB, MRCS, Giovanna L. Caxeiro MD, Richard J. Wong MD, Marc A. Cohen MD, Jatin P. Shah MD, PhD, DSc, FRCS (Hon), Snehal G. Patel MD, Ian Ganly MD\",\"doi\":\"10.1002/hed.27840\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Pleomorphic adenoma (PA) is a common parotid tumor, yet due to the relative rarity of deep lobe PA (DLPA), there is a paucity of information about its clinical presentation and surgical outcomes.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>We reviewed the charts of patients with previously untreated parotid PA between the years 1990 and 2015. Clinical parameters and surgical outcomes were compared between superficial lobe PA (SLPA) and DLPA.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>The cohort comprised 147 cases of DLPA and 222 cases of SLPA. DLPA were larger (median 2.6 cm vs. 2.0 cm, <i>p</i> < 0.001), more often discovered incidentally on imaging (33%, <i>n</i> = 48) and had unique presentations (pharyngeal mass, dysphagia, otalgia). Postsurgical complications were more frequently observed in DLPA (41% vs. 30% in SLPA, <i>p</i> = 0.025), mainly transient facial nerve weakness. DLPA also showed higher recurrence rates (<i>n</i> = 6, 4.1% vs. <i>n</i> = 1, 0.4%, <i>p</i> = 0.016).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>Parotidectomy for DLPA carries a higher risk of complications and recurrence compared to SLPA.</p>\\n </section>\\n </div>\",\"PeriodicalId\":2,\"journal\":{\"name\":\"ACS Applied Bio Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-06-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Bio Materials\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/hed.27840\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/hed.27840","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
Parotidectomy for deep lobe pleomorphic adenomas is associated with higher rates of complications and recurrence
Background
Pleomorphic adenoma (PA) is a common parotid tumor, yet due to the relative rarity of deep lobe PA (DLPA), there is a paucity of information about its clinical presentation and surgical outcomes.
Methods
We reviewed the charts of patients with previously untreated parotid PA between the years 1990 and 2015. Clinical parameters and surgical outcomes were compared between superficial lobe PA (SLPA) and DLPA.
Results
The cohort comprised 147 cases of DLPA and 222 cases of SLPA. DLPA were larger (median 2.6 cm vs. 2.0 cm, p < 0.001), more often discovered incidentally on imaging (33%, n = 48) and had unique presentations (pharyngeal mass, dysphagia, otalgia). Postsurgical complications were more frequently observed in DLPA (41% vs. 30% in SLPA, p = 0.025), mainly transient facial nerve weakness. DLPA also showed higher recurrence rates (n = 6, 4.1% vs. n = 1, 0.4%, p = 0.016).
Conclusions
Parotidectomy for DLPA carries a higher risk of complications and recurrence compared to SLPA.
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