高病毒性肺炎克雷伯氏菌向耐多药高病毒性肺炎克雷伯氏菌的进化转变：印度经验。

IF 1.4 4区医学 Q4 IMMUNOLOGY

Indian Journal of Medical Microbiology Pub Date : 2024-06-12 DOI:10.1016/j.ijmmb.2024.100619

Sanika Mahesh Kulkarni , Jobin John Jacob , V. Aravind , T. Praveen , Karthik Gunasekaran , Binesh Lal Y , Kamini Walia , Balaji Veeraraghavan

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引用次数: 0

摘要

一种新出现的肺炎克雷伯氏菌病原型最初在东南亚国家发现，现已扩散到包括印度在内的多个国家。这些同时携带耐药性和毒力决定因子的融合菌株被归类为多重耐药高病毒性肺炎克雷伯菌（MDR-HvKp）。自首次报道以来，全球范围内由这种病原体引起的感染激增，令人担忧。在此背景下，我们旨在揭示这种相对新颖的病原型所发生的进化变化。了解这些变化对于制定诊断和有针对性的干预策略以减少 MDR-HvKp 感染的传播至关重要。

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Evolutionary Transition of Hypervirulent Klebsiella pneumoniae to multidrug-resistant Hypervirulent Klebsiella pneumoniae: Indian experience

An emerging pathotype of Klebsiella pneumoniae, initially identified in Southeast Asian countries, has now spread to multiple countries, including India. These convergent strains, carrying both resistance and virulence determinants, are classified as multidrug-resistant Hypervirulent Klebsiella pneumoniae (MDR-HvKp). Since the initial reports, there has been a concerning surge in infections caused by this pathotype globally. In this context, we aim to shed light on the evolutionary changes that have taken place in this relatively novel pathotype. Understanding these changes is crucial for devising diagnosis and targeted intervention strategies to mitigate the spread of MDR-HvKp infections.

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来源期刊

Indian Journal of Medical Microbiology IMMUNOLOGY-

CiteScore

2.20

自引率

0.00%

发文量

154

审稿时长

73 days

期刊介绍： Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.