抗磷脂抗体和抗磷脂综合征。

Q4 Medicine

Ugeskrift for laeger Pub Date : 2024-05-20 DOI:10.61409/V11230715

Rasmus Søgaard Hansen, Julie Brogaard Larsen, Pernille Just Vinholt, Anne Voss, Anders Abildgaard

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引用次数: 0

摘要

抗磷脂综合征（APS）患者体内存在针对磷脂结合蛋白（aPL）的抗体。这种疾病与血栓栓塞和产科并发症的风险增加最为相关。2023 年 APS 分类标准包括六个临床领域（静脉血栓栓塞、动脉血栓形成、微血管事件、产科事件、心脏瓣膜、血小板减少症）和两个实验室领域（狼疮抗凝物、抗心磷脂或抗β2-糖蛋白-I 抗体）。APS 的诊断和治疗是一项专业任务，本综述对此进行了总结。

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Antiphospholipid antibodies and antiphospholipid syndrome.

Individuals with antiphospholipid syndrome (APS) have antibodies directed against phospholipid-binding proteins (aPL). The condition is most associated with an increased risk of thromboembolism and obstetric complications. The 2023 classification criteria for APS include six clinical domains (venous thromboembolism, arterial thrombosis, microvascular events, obstetric events, cardiac valve, thrombocytopaenia) and two laboratory domains (lupus anticoagulant, and anti-cardiolipin or anti-β2-glycoprotein-I antibodies). Diagnosis and treatment of APS are specialist tasks and are summarised in this review.

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来源期刊

Ugeskrift for laeger Medicine-Medicine (all)

CiteScore

0.20

自引率

0.00%

发文量

345

期刊介绍： The Ulster Medical Journal is an international general medical journal with contributions on all areas of medical and surgical specialties relevant to a general medical readership. It retains a focus on material relevant to the health of the Northern Ireland population. The Honorary Editor would welcome offers of papers for publication. Prospective authors are invited to read the notice to contributors.