ph 对磺胺甲基嘧啶在土壤系统中迁移模式和降解途径的影响。

IF 1.4 4区 农林科学 Q4 ENVIRONMENTAL SCIENCES
Xin Li, Haifang Wang, Zhumei Sun, Xia Cao, Junli Zhang, Qihua Chen, Rui Ma
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引用次数: 0

摘要

磺胺类抗生素(SAs)是畜牧业和水产养殖业广泛使用的抗菌剂,进入动物体内的大部分抗生素会以原药或代谢物的形式释放到环境中,最终通过食物链影响人类健康。土壤的酸沉积和盐碱化都可能对抗生素的迁移和降解产生影响。磺胺二甲嘧啶(SM2)是农业土壤中经常检测到的一种化合物,其在环境中的迁移和转化过程与环境 pH 值密切相关。然而,有关土壤 pH 值变化对磺胺二甲嘧啶环境行为影响的研究却很少。我们利用模拟实验和超高效液相色谱-四极杆飞行时间质谱(UHPLC-Q-TOF-MS)技术分析了 SM2 的迁移和降解机制。结果表明,酸性条件限制了磺胺二甲嘧啶的垂直迁移,SM2在不同的pH条件下发生了不同的反应过程,包括S-C键断裂、S-N键水解、去甲基化、六元杂环加成、甲基羟基化和开环。研究SM2在不同pH条件下的迁移规律和降解机理,可为评估酸雨和盐碱条件下磺胺甲基嘧啶降解产物的污染风险提供坚实的理论依据,为抗生素污染修复提供指导,从而更好地防控和保护地下水资源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of ph on migration patterns and degradation pathways of sulfamethazine in soil systems.

Sulfonamide antibiotics (SAs) are widely used antimicrobial agents in livestock and aquaculture, and most of them entering the animal's body will be released into the environment as prodrugs or metabolites, which ultimately affect human health through the food chain. Both acid deposition and salinization of soil may have an impact on the migration and degradation of antibiotics. Sulfamethazine (SM2), a frequently detected compound in agricultural soils, has a migration and transformation process in the environment that is closely dependent on environmental pH. Nevertheless, scarcely any studies have been conducted on the effect of soil pH changes on the environmental behavior of sulfamethazine. We analyzed the migration and degradation mechanisms of SM2 using simulation experiments and ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) techniques. The results showed that acidic conditions limited the vertical migration of sulfadimidine, and SM2 underwent different reaction processes under different pH conditions, including S-C bond breaking, S-N bond hydrolysis, demethylation, six-membered heterocyclic addition, methyl hydroxylation and ring opening. The study of the migration pattern and degradation mechanism of SM2 under different pH conditions can provide a solid theoretical basis for assessing the pollution risk of sulfamethazine degradation products under acid rain and saline conditions, and provide a guideline for remediation of antibiotic contamination, so as to better prevent, control and protect groundwater resources.

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来源期刊
CiteScore
4.00
自引率
5.00%
发文量
87
审稿时长
1 months
期刊介绍: 12 issues per year Abstracted/indexed in: Agricola; Analytical Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; BioSciences Information Service of Biological Abstracts (BIOSIS); CAB Abstracts; CAB AGBiotech News and Information; CAB Irrigation & Drainage Abstracts; CAB Soils & Fertilizers Abstracts; Chemical Abstracts Service Plus; CSA Aluminum Industry Abstracts; CSA ANTE: Abstracts in New Technology and Engineering; CSA ASFA 3 Aquatic Pollution and Environmental Quality; CSA ASSIA: Applied Social Sciences Index & Abstracts; CSA Ecology Abstracts; CSA Entomology Abstracts; CSA Environmental Engineering Abstracts; CSA Health & Safety Science Abstracts; CSA Pollution Abstracts; CSA Toxicology Abstracts; CSA Water Resource Abstracts; EBSCOhost Online Research Databases; Elsevier BIOBASE/Current Awareness in Biological Sciences; Elsevier Engineering Information: EMBASE/Excerpta Medica/ Engineering Index/COMPENDEX PLUS; Environment Abstracts; Environmental Knowledge; Food Science and Technology Abstracts; Geo Abstracts; Geobase; Food Science; Index Medicus/ MEDLINE; INIST-Pascal/ CNRS; NIOSHTIC; ISI BIOSIS Previews; Pesticides; Food Contaminants and Agricultural Wastes: Analytical Abstracts; Pollution Abstracts; PubSCIENCE; Reference Update; Research Alert; Science Citation Index Expanded (SCIE); and Water Resources Abstracts.
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