儿科人群中爱泼斯坦-巴氏病毒的血清流行率和特征。

IF 1.4 4区医学 Q4 IMMUNOLOGY

Indian Journal of Medical Microbiology Pub Date : 2024-06-08 DOI:10.1016/j.ijmmb.2024.100643

Praroop Garg, Monika Matlani, Shilpee Kumar, Deepthi Nair

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引用次数: 0

摘要

该研究利用 EBV 特异性血清学检测了 244 名德里儿童的 EBV 暴露情况。EBV 血清阳性率为 75-80%。52.04%的儿童曾感染过EBV，8.6%的儿童初次感染过EBV，而23.36%的儿童没有EBV血清学证据。年龄分层表明，6 个月大的婴儿可能已受到母体抗体的保护，而 1-3 岁年龄组的原发性感染率最高，6 个月至 1 岁年龄组是 EBV 原发性感染的最大易感人群。有关印度 EBV 的文献很少，需要进一步研究，以更好地了解 EBV 的发病机制及其对印度儿童的临床影响。

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Seroprevalence and characterization of Epstein-Barr virus exposure among paediatric population

The study explored Epstein Barr Virus (EBV) exposure in 244 children using EBV-specific serology. Seroprevalence of EBV was 75–80%. Past infection and primary infection were observed in 52.04% & 8.6% respectively, whereas 23.36% showed no serological evidence of exposure to EBV. Age-stratification suggested maternal antibodies may have protected infants till 6 months of age, while the 1–3 year age group showed maximum primary infection and the 6 months to 1 year group showed the maximum susceptible group to EBV primary infection. There is a paucity of literature about EBV in India and further research is required for a better understanding of EBV pathogenesis and its clinical implications in Indian children.

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来源期刊

Indian Journal of Medical Microbiology IMMUNOLOGY-

CiteScore

2.20

自引率

0.00%

发文量

154

审稿时长

73 days

期刊介绍： Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.