使用生物发光计比较评估 1%和 3%次氯酸钠对减少基牙根管微生物数量的功效--随机临床试验

IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE
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引用次数: 0

摘要

目的次氯酸钠(NaOCl)通常用于在牙髓切除术中冲洗基牙。虽然高浓度的 NaOCl 很有效,但如果 NaOCl 穿透根尖孔,就有可能对根尖周组织造成毒性损伤。因此,人们倾向于使用低浓度的 NaOCl 来降低这种风险。然而,与高浓度相比,低浓度 NaOCl 的抗菌效果仍然令人担忧。本研究的目的是评估和比较 1%和 3% NaOCl 冲洗对减少基牙根管内细菌负荷的功效。第一组(n = 20)接受 1 % NaOCl 溶液的根管冲洗,第二组(n = 20)接受 3 % NaOCl 溶液的根管冲洗。在灌洗前和灌洗后,用纸点从根管采集微生物样本。将样本无菌转移到超速管中,然后用生物发光仪进行分析。结果两组在灌洗后细菌数量都有所减少。3 % NaOCl 冲洗后的平均菌落数为 258.05 ± 28.61,而 1 % NaOCl 冲洗后的平均菌落数为 267.60 ± 30.56。结论 本研究表明,1% NaOCl 和 3% NaOCl 在减少根管内细菌数量方面具有相同的效果。因此,在临床实践中使用 1%NaOCl 作为冲洗剂是合适的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative evaluation of the efficacy of 1% and 3% Sodium hypochlorite in reducing the microbial counts in primary teeth root canals using Bioluminometer – A randomized clinical trial

Purpose

Sodium hypochlorite (NaOCl) is commonly used to irrigate primary teeth during pulpectomy. Although high concentrations of NaOCl are effective, they pose a risk of toxic damage to periapical tissues if NaOCl penetrates through the apical foramen. Therefore, low concentrations of NaOCl are preferred to mitigate this risk. However, concerns persist regarding the antibacterial efficacy of low concentrations of NaOCl compared to high concentrations. The objective of this study was to assess and compare the efficacy of 1% and 3% NaOCl irrigation in reducing bacterial load within primary teeth root canals.

Materials and methods

This clinical study involved forty participants divided into two groups. Group 1 (n = 20) received canal irrigation with 1 % NaOCl solution, while Group 2 (n = 20) received canal irrigation with 3 % NaOCl solution. Microbial samples were collected from the root canal using a paper point before and after irrigation. The samples were aseptically transferred to ultra-snap tubes and then analyzed using a Bioluminometer. The results were recorded.

Results

Both groups exhibited a decrease in bacterial count after irrigation. The mean colony count post irrigation for 3 % NaOCl was 258.05 ± 28.61, and for 1 % NaOCl it was 267.60 ± 30.56. However, no statistically significant difference was observed upon intergroup comparison.

Conclusion

This study shows that 1% NaOCl is equally effective as 3% NaOCl in reducing bacterial count in root canals. Thus, using 1% NaOCl as an irrigant is appropriate in clinical practice.

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来源期刊
Saudi Dental Journal
Saudi Dental Journal DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
3.60
自引率
0.00%
发文量
86
审稿时长
22 weeks
期刊介绍: Saudi Dental Journal is an English language, peer-reviewed scholarly publication in the area of dentistry. Saudi Dental Journal publishes original research and reviews on, but not limited to: • dental disease • clinical trials • dental equipment • new and experimental techniques • epidemiology and oral health • restorative dentistry • periodontology • endodontology • prosthodontics • paediatric dentistry • orthodontics and dental education Saudi Dental Journal is the official publication of the Saudi Dental Society and is published by King Saud University in collaboration with Elsevier and is edited by an international group of eminent researchers.
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