Design and simulation of a resonant nanoring-based two-dimensional photonic crystal biosensor for cancer cell detection

This article introduces a novel two-dimensional photonic crystal biosensor designed for the detection of various cancer cell types and the verification of associated parameters. The proposed structure features a circular resonator nanoring with a sensing region at its center, facilitating the connection with cancer cells. The sensor has been tested with a diverse range of cancer cell types including skin, cervical, blood, adrenal, and two subtypes of breast cancer cells (Sort 1 and Sort 2). All outputs of the structure were studied at two different wavelengths and its parameters were analyzed separately. The best quality factor obtained for normal and abnormal cells of the target structure is 13,353 and 3053, respectively. Due to its high-quality factor and high FOM and low DL, this sensor has an acceptable sensitivity of 214.28(nm/RIU). FOM and DL in this sensor are equal to 172.35(RIU⁻¹) and 5.80 × 10⁻⁴(RIU), respectively. The resonant wavelength shift of this structure is a relatively good value due to the coupling distance between the input wave and the resonator nanoring.