Anfisa Ayalon, Fidaa El Zhalka, Alexander Rubowitz, P. Roy, S. Shoval, I. Legchenkova, E. Bormashenko
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Wetting of the retinal surface by perfluorocarbon liquid: implications for its use as an endotamponade agent and intraoperative tool in retinal detachment surgery
Perfluorocarbon liquids (PFCLs) are essential in ophthalmology due to their unique properties, such as higher density than water, inert chemical nature, and optical transparency. They serve as crucial tools in retinal detachment surgery, acting as both intraoperative aids and short-term tamponade agents. However, the interactions between PFCLs and the retinal surface are not fully understood, limiting insights into potential complications. This study investigates the interfacial interaction between perfluorodecalin (PFCL) and the retinal surface. Wetting behavior of animal retinas by water and PFCL was analyzed, revealing water droplets’ floating phenomenon in PFCL and calculating the critical radius for this effect. Dynamics of water spreading over the retina were examined. A model experiment demonstrated that water’s tendency to float over PFCL, interacting with a hydrophilic surface like the retina, could create traction and damage the retinal surface. These findings enhance our comprehension of physical processes at the PFCL/retina interface and offer practical insights for improving ophthalmic surgical procedures.
期刊介绍:
ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications.
The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.