来自干细胞的心脏和血管偶然和好运的简史

IF 3.2 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

BioEssays Pub Date : 2024-06-05 DOI:10.1002/bies.202400078

Christine Mummery

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引用次数: 0

摘要

干细胞研究是实验室和学科之间以及实验室和学科内部日积月累、共同努力的产物。许多合作步骤导致了特殊的 "尤里卡时刻"，当多年的谜题突然变得清晰时，这是科学生涯中最大的乐趣之一。本文将描述从初识多能干细胞到研究发育和疾病过程中出现的先进心血管模型的偶然途径。或许对后代干细胞研究人员的启发仅仅是追随他们觉得有趣的东西。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Heart and vessels from stem cells: A short history of serendipity and good luck

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Heart and vessels from stem cells: A short history of serendipity and good luck

Stem cell research is the product of cumulative, integrated effort between and within laboratories and disciplines. The many collaborative steps that lead to that special “Eureka moment”, when something that has been a puzzle perhaps for years suddenly become clear, is among the greatest pleasures of a scientific career. In this essay, the serendipitous pathway from first acquaintance with pluripotent stem cells to advanced cardiovascular models that emerged from studying development and disease will be described. Perhaps inspiration for later generations of stem cell researchers simply to follow whatever they find interesting.

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来源期刊

BioEssays 生物-生化与分子生物学

CiteScore

7.30

自引率

2.50%

发文量

167

审稿时长

4-8 weeks

期刊介绍： molecular – cellular – biomedical – physiology – translational research – systems - hypotheses encouraged BioEssays is a peer-reviewed, review-and-discussion journal. Our aims are to publish novel insights, forward-looking reviews and commentaries in contemporary biology with a molecular, genetic, cellular, or physiological dimension, and serve as a discussion forum for new ideas in these areas. An additional goal is to encourage transdisciplinarity and integrative biology in the context of organismal studies, systems approaches, through to ecosystems, where appropriate.