用具有 pH 响应性的β-葡聚糖衍生物修饰的脂质体的大小对在小鼠模型中启动细胞和体液免疫反应的影响

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-31 DOI:10.1080/13102818.2024.2358992

Shin Yanagihara, Eiji Yuba, Atsushi Harada

引用次数: 0

摘要

尺寸是抗原载体的重要因素之一，因为它会影响细胞相互作用、药代动力学、免疫细胞活化和免疫反应类型。我们开发了pH-sen...

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The impact of size for liposomes modified with pH-responsive β-glucan derivatives on the initiation of cellular and humoral immune responses in murine models

Size is one of the important factors for antigen carriers because it influences cellular interaction, pharmacokinetics, immune cell activation and the types of immune responses. We developed pH-sen...

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.