Trenton K. Stewart , Ines E. Carotti , Yasser M. Qureshi , James A. Covington
{"title":"用于无创呼吸分析的化学传感器的发展趋势","authors":"Trenton K. Stewart , Ines E. Carotti , Yasser M. Qureshi , James A. Covington","doi":"10.1016/j.trac.2024.117792","DOIUrl":null,"url":null,"abstract":"<div><p>The advancements of chemical sensors over the past 50 years have significantly expanded the diversity of available sensors making them more affordable, portable, sensitive, and partially chemically selective. Despite these advancements, the diversity and capability of sensors used in breath analysis has remained limited due to challenges that persist in this field. This encompasses fluctuations in humidity, temperature, and oxygen concentration within breath that all pose challenges that can significantly affect sensor output. This review article aims to introduce and compare the techniques used in current chemical sensor arrays for breath analysis. A brief overview of the discrete chemical sensors and arrays employed in breath research, at both commercial and research levels, is discussed. Furthermore, current trends in data analysis for chemical sensor arrays in breath analysis is described. Finally, a detailed outlook of recent diagnostic results from studies implementing sensor arrays from the last 5 years is outlined.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8000,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0165993624002759/pdfft?md5=8a08c0219137006ccaa2a60050b63175&pid=1-s2.0-S0165993624002759-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Trends in chemical sensors for non-invasive breath analysis\",\"authors\":\"Trenton K. Stewart , Ines E. Carotti , Yasser M. Qureshi , James A. Covington\",\"doi\":\"10.1016/j.trac.2024.117792\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The advancements of chemical sensors over the past 50 years have significantly expanded the diversity of available sensors making them more affordable, portable, sensitive, and partially chemically selective. Despite these advancements, the diversity and capability of sensors used in breath analysis has remained limited due to challenges that persist in this field. This encompasses fluctuations in humidity, temperature, and oxygen concentration within breath that all pose challenges that can significantly affect sensor output. This review article aims to introduce and compare the techniques used in current chemical sensor arrays for breath analysis. A brief overview of the discrete chemical sensors and arrays employed in breath research, at both commercial and research levels, is discussed. Furthermore, current trends in data analysis for chemical sensor arrays in breath analysis is described. Finally, a detailed outlook of recent diagnostic results from studies implementing sensor arrays from the last 5 years is outlined.</p></div>\",\"PeriodicalId\":439,\"journal\":{\"name\":\"Trends in Analytical Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":11.8000,\"publicationDate\":\"2024-05-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S0165993624002759/pdfft?md5=8a08c0219137006ccaa2a60050b63175&pid=1-s2.0-S0165993624002759-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Analytical Chemistry\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0165993624002759\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993624002759","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Trends in chemical sensors for non-invasive breath analysis
The advancements of chemical sensors over the past 50 years have significantly expanded the diversity of available sensors making them more affordable, portable, sensitive, and partially chemically selective. Despite these advancements, the diversity and capability of sensors used in breath analysis has remained limited due to challenges that persist in this field. This encompasses fluctuations in humidity, temperature, and oxygen concentration within breath that all pose challenges that can significantly affect sensor output. This review article aims to introduce and compare the techniques used in current chemical sensor arrays for breath analysis. A brief overview of the discrete chemical sensors and arrays employed in breath research, at both commercial and research levels, is discussed. Furthermore, current trends in data analysis for chemical sensor arrays in breath analysis is described. Finally, a detailed outlook of recent diagnostic results from studies implementing sensor arrays from the last 5 years is outlined.
期刊介绍:
TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.