人道终点，已定义。

IF 5.9 3区农林科学 Q1 VETERINARY SCIENCES

Lab Animal Pub Date : 2024-06-04 DOI:10.1038/s41684-024-01378-3

Lauren Danridge, Bill Greer, Samantha Sullivan, Obed Rutebuka, Louis DiVincenti, Axel Wolff

{"title":"人道终点，已定义。","authors":"Lauren Danridge, Bill Greer, Samantha Sullivan, Obed Rutebuka, Louis DiVincenti, Axel Wolff","doi":"10.1038/s41684-024-01378-3","DOIUrl":null,"url":null,"abstract":"Animals used in biomedical research may experience pain or distress as part of the experimental protocol. By implementing humane endpoints, pain or distress can be prevented or alleviated whilst still meeting scientific aims and objectives. We invited experts from Arizona State University (Samantha Sullivan) and Loma Linda University (Obed Rutebuka), along with USDA and OLAW representatives (Louis DiVincenti and Axel Wolff), to respond to a scenario about the importance of defining humane endpoints in research protocols.","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 6","pages":"123-125"},"PeriodicalIF":5.9000,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Humane endpoints, defined\",\"authors\":\"Lauren Danridge, Bill Greer, Samantha Sullivan, Obed Rutebuka, Louis DiVincenti, Axel Wolff\",\"doi\":\"10.1038/s41684-024-01378-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Animals used in biomedical research may experience pain or distress as part of the experimental protocol. By implementing humane endpoints, pain or distress can be prevented or alleviated whilst still meeting scientific aims and objectives. We invited experts from Arizona State University (Samantha Sullivan) and Loma Linda University (Obed Rutebuka), along with USDA and OLAW representatives (Louis DiVincenti and Axel Wolff), to respond to a scenario about the importance of defining humane endpoints in research protocols.\",\"PeriodicalId\":17936,\"journal\":{\"name\":\"Lab Animal\",\"volume\":\"53 6\",\"pages\":\"123-125\"},\"PeriodicalIF\":5.9000,\"publicationDate\":\"2024-06-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lab Animal\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.nature.com/articles/s41684-024-01378-3\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lab Animal","FirstCategoryId":"97","ListUrlMain":"https://www.nature.com/articles/s41684-024-01378-3","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}

引用次数: 0

摘要

作为实验方案的一部分，生物医学研究中使用的动物可能会经历疼痛或痛苦。通过实施人道终点，可以防止或减轻疼痛或痛苦，同时还能达到科学目的和目标。我们邀请了亚利桑那州立大学（Samantha Sullivan）和洛马琳达大学（Obed Rutebuka）的专家，以及美国农业部和法律事务厅（OLAW）的代表（Louis DiVincenti 和 Axel Wolff），就研究方案中定义人道终点的重要性进行了情景模拟。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Humane endpoints, defined

Animals used in biomedical research may experience pain or distress as part of the experimental protocol. By implementing humane endpoints, pain or distress can be prevented or alleviated whilst still meeting scientific aims and objectives. We invited experts from Arizona State University (Samantha Sullivan) and Loma Linda University (Obed Rutebuka), along with USDA and OLAW representatives (Louis DiVincenti and Axel Wolff), to respond to a scenario about the importance of defining humane endpoints in research protocols.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Lab Animal 农林科学-兽医学

CiteScore

0.60

自引率

2.90%

发文量

181

审稿时长

>36 weeks

期刊介绍： LabAnimal is a Nature Research journal dedicated to in vivo science and technology that improves our basic understanding and use of model organisms of human health and disease. In addition to basic research, methods and technologies, LabAnimal also covers important news, business and regulatory matters that impact the development and application of model organisms for preclinical research. LabAnimal's focus is on innovative in vivo methods, research and technology covering a wide range of model organisms. Our broad scope ensures that the work we publish reaches the widest possible audience. LabAnimal provides a rigorous and fair peer review of manuscripts, high standards for copyediting and production, and efficient publication.