通过咪唑并[1,2-a]吡啶与氯烃衍生物的弗里德尔-卡夫斯反应合成无过渡金属的三芳基甲烷

IF 5.8 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Journal of Saudi Chemical Society Pub Date : 2024-05-29 DOI:10.1016/j.jscs.2024.101883

Xinlei Fu , Longhui Wu , Xiaohua Guo, Kai Yang, Zhaowen Liu

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引用次数: 0

摘要

本研究描述了一种通过咪唑并[1,2-a]吡啶与氯烃衍生物的直接弗里德尔-卡夫斯反应合成三芳基甲烷的简便、无过渡金属、HFIP 促成的方法，该方法可在室温下高效合成含有咪唑并[1,2-a]吡啶的三芳基甲烷，收率良好甚至令人满意。这种转化方法具有操作简单、官能团耐受性好和底物范围广的特点。

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Transition-metal-free synthesis of triarylmethanes via Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives

A facile, transition-metal-free, HFIP-promoted method for the synthesis of triarylmethanes through direct Friedel-Crafts reactions of imidazo[1,2-a]pyridines with chlorohydrocarbon derivatives has been described, which allows for efficient synthesis of triarylmethanes containing imidazo[1,2-a]pyridines in good to satisfactory yields at room temperature. This transformation features simple operation, excellent functional group tolerance, and a broad substrate scope.

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来源期刊

Journal of Saudi Chemical Society CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

8.90

自引率

1.80%

发文量

120

审稿时长

38 days

期刊介绍： Journal of Saudi Chemical Society is an English language, peer-reviewed scholarly publication in the area of chemistry. Journal of Saudi Chemical Society publishes original papers, reviews and short reports on, but not limited to: •Inorganic chemistry •Physical chemistry •Organic chemistry •Analytical chemistry Journal of Saudi Chemical Society is the official publication of the Saudi Chemical Society and is published by King Saud University in collaboration with Elsevier and is edited by an international group of eminent researchers.