Jamilah S AlRahimi, Yasser M Ismail, Noor A Aljubairi, Nawal W Kutob, Ghadi S Bakulka, Ruqayyah A Ahmed, Fatima A Ahmed, Ali A Haneef
{"title":"评估三尖瓣反流程度与肺动脉高压之间的相关性:一项综合研究","authors":"Jamilah S AlRahimi, Yasser M Ismail, Noor A Aljubairi, Nawal W Kutob, Ghadi S Bakulka, Ruqayyah A Ahmed, Fatima A Ahmed, Ali A Haneef","doi":"10.15537/smj.2024.45.6.20240071","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the relationship between severity of tricuspid regurgitation (TR) and pulmonary hypertension.</p><p><strong>Methods: </strong>Cross-sectional study of 118 patients with pulmonary hypertension was carried out at a single center in Jeddah, Saudi Arabia, between 2018-2021. Patients who had pulmonary or tricuspid valves organic diseases, previously undergone tricuspid or pulmonary valve surgeries, had permanent pacemakers or critically ill were excluded.</p><p><strong>Results: </strong>A high proportion of patients were women (n=100, 85%) and obese (n=57, 48%). Patients with more than mild TR had higher systolic pulmonary artery pressure (sPAP) than those with trivial or mild regurgitation (<i>p</i><0.001). There was a significant association between severity of TR (<i>p</i><0.001) and right chambers size (<i>p</i>=0.001). Furthermore, pulmonary artery pressure (PAP) was significantly higher in patients with mild right ventricular impairment (<i>p</i>=0.001).</p><p><strong>Conclusion: </strong>Increase in degree of TR and right atrial size were predictors of elevated sPAP. Our findings highlight the interplay among TR, right heart size, ventricular function, and PAP. Understanding these associations can aid in risk stratification, monitoring disease progression, and potentially guiding treatment in those patients.</p>","PeriodicalId":21453,"journal":{"name":"Saudi Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147589/pdf/","citationCount":"0","resultStr":"{\"title\":\"Assessing the correlation between the degree of tricuspid regurgitation and pulmonary hypertension: A comprehensive study.\",\"authors\":\"Jamilah S AlRahimi, Yasser M Ismail, Noor A Aljubairi, Nawal W Kutob, Ghadi S Bakulka, Ruqayyah A Ahmed, Fatima A Ahmed, Ali A Haneef\",\"doi\":\"10.15537/smj.2024.45.6.20240071\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To evaluate the relationship between severity of tricuspid regurgitation (TR) and pulmonary hypertension.</p><p><strong>Methods: </strong>Cross-sectional study of 118 patients with pulmonary hypertension was carried out at a single center in Jeddah, Saudi Arabia, between 2018-2021. Patients who had pulmonary or tricuspid valves organic diseases, previously undergone tricuspid or pulmonary valve surgeries, had permanent pacemakers or critically ill were excluded.</p><p><strong>Results: </strong>A high proportion of patients were women (n=100, 85%) and obese (n=57, 48%). Patients with more than mild TR had higher systolic pulmonary artery pressure (sPAP) than those with trivial or mild regurgitation (<i>p</i><0.001). There was a significant association between severity of TR (<i>p</i><0.001) and right chambers size (<i>p</i>=0.001). Furthermore, pulmonary artery pressure (PAP) was significantly higher in patients with mild right ventricular impairment (<i>p</i>=0.001).</p><p><strong>Conclusion: </strong>Increase in degree of TR and right atrial size were predictors of elevated sPAP. Our findings highlight the interplay among TR, right heart size, ventricular function, and PAP. Understanding these associations can aid in risk stratification, monitoring disease progression, and potentially guiding treatment in those patients.</p>\",\"PeriodicalId\":21453,\"journal\":{\"name\":\"Saudi Medical Journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147589/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Saudi Medical Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.15537/smj.2024.45.6.20240071\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Saudi Medical Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.15537/smj.2024.45.6.20240071","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Assessing the correlation between the degree of tricuspid regurgitation and pulmonary hypertension: A comprehensive study.
Objectives: To evaluate the relationship between severity of tricuspid regurgitation (TR) and pulmonary hypertension.
Methods: Cross-sectional study of 118 patients with pulmonary hypertension was carried out at a single center in Jeddah, Saudi Arabia, between 2018-2021. Patients who had pulmonary or tricuspid valves organic diseases, previously undergone tricuspid or pulmonary valve surgeries, had permanent pacemakers or critically ill were excluded.
Results: A high proportion of patients were women (n=100, 85%) and obese (n=57, 48%). Patients with more than mild TR had higher systolic pulmonary artery pressure (sPAP) than those with trivial or mild regurgitation (p<0.001). There was a significant association between severity of TR (p<0.001) and right chambers size (p=0.001). Furthermore, pulmonary artery pressure (PAP) was significantly higher in patients with mild right ventricular impairment (p=0.001).
Conclusion: Increase in degree of TR and right atrial size were predictors of elevated sPAP. Our findings highlight the interplay among TR, right heart size, ventricular function, and PAP. Understanding these associations can aid in risk stratification, monitoring disease progression, and potentially guiding treatment in those patients.
期刊介绍:
The Saudi Medical Journal is a monthly peer-reviewed medical journal. It is an open access journal, with content released under a Creative Commons attribution-noncommercial license.
The journal publishes original research articles, review articles, Systematic Reviews, Case Reports, Brief Communication, Brief Report, Clinical Note, Clinical Image, Editorials, Book Reviews, Correspondence, and Student Corner.