男性性腺功能与男性整体健康之间的相互作用

Q3 Pharmacology, Toxicology and Pharmaceutics
Vincenzo Asero, Carlo Maria Scornajenghi, Salvatore Iaconis, Enrico Sicignano, Alfonso Falcone, Fabrizio Dinacci, Giovanni Pagano, Dalila Carino, Roberta Corvino, Anas Tresh
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引用次数: 0

摘要

男性生殖过程错综复杂,各种疾病都有可能破坏精子的生成。此外,男性不育可作为未来潜在健康问题的指标。目前已发现许多具有系统性影响的疾病,包括遗传因素(如克雷菲尔特综合征)、肥胖、心理压力、环境因素等。因此,不孕不育评估为全面的健康咨询提供了一个机会,而不仅仅是关于生育目标的讨论。此外,男性不育被认为是未来健康问题的先兆,因为精液质量差和男性不育的诊断与性腺功能低下、心脏代谢紊乱、癌症甚至死亡的风险增加有关。本综述探讨了有关全身性疾病与男性生育能力之间关系的现有文献,这些疾病对临床结果和精液参数都有影响。所分析的大部分文献将性腺功能与遗传、慢性、传染性或肿瘤性疾病进行了比较,证实了男性整体健康与不育之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Interplay between male gonadal function and overall male health.

The process-of-male reproduction is intricate, and various medical conditions-have the potential to disrupt spermatogenesis. Moreover, infertility in males can serve as an indicator of-potential future health issue. Numerous conditions with systemic implications have been identified, encompassing genetic factors (such as Klinefelter Syndrome), obesity, psychological stress, environmental factors, and others. Consequently, infertility assessment-presents an opportunity for comprehensive health counseling, extending-beyond discussions about reproductive goals. Furthermore, male infertility has been suggested as a harbinger of future health problems, as poor semen quality and a diagnosis of-male infertility are associated with an increased risk of hypogonadism, cardiometabolic disorders, cancer, and even mortality. This review explores the existing-literature on the relationship between systemic illnesses and male fertility, impacting both clinical-outcomes and semen parameters. The majority of the literature analyzed, which compared gonadal function with genetic, chronic, infectious or tumoral diseases, confirm the association between overall male health and infertility.

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来源期刊
Journal of Basic and Clinical Physiology and Pharmacology
Journal of Basic and Clinical Physiology and Pharmacology Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
3.90
自引率
0.00%
发文量
53
期刊介绍: The Journal of Basic and Clinical Physiology and Pharmacology (JBCPP) is a peer-reviewed bi-monthly published journal in experimental medicine. JBCPP publishes novel research in the physiological and pharmacological sciences, including brain research; cardiovascular-pulmonary interactions; exercise; thermal control; haematology; immune response; inflammation; metabolism; oxidative stress; and phytotherapy. As the borders between physiology, pharmacology and biochemistry become increasingly blurred, we also welcome papers using cutting-edge techniques in cellular and/or molecular biology to link descriptive or behavioral studies with cellular and molecular mechanisms underlying the integrative processes. Topics: Behavior and Neuroprotection, Reproduction, Genotoxicity and Cytotoxicity, Vascular Conditions, Cardiovascular Function, Cardiovascular-Pulmonary Interactions, Oxidative Stress, Metabolism, Immune Response, Hematological Profile, Inflammation, Infection, Phytotherapy.
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