超加工食品：增加炎症和免疫失调的风险？

IF 67.7 1区医学 Q1 IMMUNOLOGY

Nature Reviews Immunology Pub Date : 2024-06-03 DOI:10.1038/s41577-024-01049-x

Katherine A. Maki, Michael N. Sack, Kevin D. Hall

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引用次数: 0

摘要

超加工食品（UPFs）是工业配制的产品，含有合成成分，但全食品成分极少。UPF含量高的饮食与免疫调节失调相关疾病的风险增加有关，如炎症性肠病和潜在的自身免疫性疾病。人们提出了几种可能的机制来解释这种关联，这些机制亟需研究关注。本评论讨论了超强加工食品（UPFs）对免疫系统的潜在影响，这些影响与肥胖无关，超强加工食品可能通过这些影响使肠道微生物群和免疫细胞之间的平衡失调。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Ultra-processed foods: increasing the risk of inflammation and immune dysregulation?

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Ultra-processed foods: increasing the risk of inflammation and immune dysregulation?

Ultra-processed foods (UPFs) are industrially formulated products that contain synthetic ingredients but minimal whole-food components. Diets high in UPFs are associated with increased risk of immune dysregulation-linked diseases such as inflammatory bowel disease and potentially autoimmune disease. Several putative mechanisms have been proposed to explain this association, and these need urgent research attention. This Comment discusses the potential effects of ultra-processed foods (UPFs) on the immune system independently of obesity, by which UPFs might dysregulate the balance between the gut microbiota and immune cells.

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来源期刊

Nature Reviews Immunology 医学-免疫学

CiteScore

93.40

自引率

0.40%

发文量

131

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Immunology is a journal that provides comprehensive coverage of all areas of immunology, including fundamental mechanisms and applied aspects. It has two international standard serial numbers (ISSN): 1474-1733 for print and 1474-1741 for online. In addition to review articles, the journal also features recent developments and new primary papers in the field, as well as reflections on influential people, papers, and events in the development of immunology. The subjects covered by Nature Reviews Immunology include allergy and asthma, autoimmunity, antigen processing and presentation, apoptosis and cell death, chemokines and chemokine receptors, cytokines and cytokine receptors, development and function of cells of the immune system, haematopoiesis, infection and immunity, immunotherapy, innate immunity, mucosal immunology and the microbiota, regulation of the immune response, signalling in the immune system, transplantation, tumour immunology and immunotherapy, and vaccine development.