甲状腺细针穿刺的流程改进:标准化涂片数量,提高充分性和诊断率。

IF 1 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY
Patrick Morse MD, Kaleigh F. Roberts MD, PhD, Nicholas C. Spies MD, Vijayalakshmi Padmanabhan MPH, MBBS
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引用次数: 0

摘要

细针穿刺术(FNA)是用于评估甲状腺结节的一种安全、经济有效的诊断方法。在过去几年中,甲状腺 FNA 的数量急剧增加。由于缺乏诊断所需穿刺针数的标准化程序,以及传统涂片(CS)与液基制剂(LBP)的使用方法不明确,甲状腺 FNA 的需求导致细胞学实验室的工作量增加,从而对患者的安全产生了负面影响。我们对 CS 实施了标准化的两针穿刺,并收集了 ThinPrep LBP 的所有针头冲洗液和额外的穿刺材料CytoRich Red,比较了干预前后的非诊断率和诊断率。干预前有 290 例,干预后有 348 例;其中干预前组有 17 例(5.9%)未诊断,干预后组有 27 例(7.8%)未诊断。干预前后的非诊断率和诊断率在统计学上没有显著差异(经双尾 Z 检验,P = 0.347)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Process improvement in thyroid fine needle aspiration: Standardizing number of smears for enhanced adequacy and diagnosis

Fine-needle aspiration (FNA) is a safe, cost-effective diagnostic procedure used in the evaluation of thyroid nodules. The number of thyroid FNAs has dramatically increased over the past few years. In the absence of standardized procedures regarding the number of needle passes needed for diagnosis and the lack of clarity on the use of conventional smears (CS) versus liquid-based preparations (LBP), the demand of thyroid FNAs has led to increased workload on cytology laboratories, which can negatively affect patient safety. We implemented a standardized two needle passes for CS and collection of all needle rinses and additional pass material in CytoRich Red for ThinPrep LBP and compared the non-diagnostic and diagnostic rates before and after this intervention. There were 290 pre-intervention cases and 348 post-intervention cases; of which, there were 17 (5.9%) non-diagnostic cases of the pre-intervention group and 27 (7.8) non-diagnostic cases of the post-intervention group. There was no statistically significant difference in non-diagnostic and diagnostic rates before and after the change (p = 0.347 by two-tailed Z test).

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来源期刊
Diagnostic Cytopathology
Diagnostic Cytopathology 医学-病理学
CiteScore
2.60
自引率
7.70%
发文量
163
审稿时长
3-6 weeks
期刊介绍: Diagnostic Cytopathology is intended to provide a forum for the exchange of information in the field of cytopathology, with special emphasis on the practical, clinical aspects of the discipline. The editors invite original scientific articles, as well as special review articles, feature articles, and letters to the editor, from laboratory professionals engaged in the practice of cytopathology. Manuscripts are accepted for publication on the basis of scientific merit, practical significance, and suitability for publication in a journal dedicated to this discipline. Original articles can be considered only with the understanding that they have never been published before and that they have not been submitted for simultaneous review to another publication.
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