Mukharram M. Bikbov, Gyulli M. Kazakbaeva, Ellina M. Rakhimova, Songhomitra Panda-Jonas, Albina A. Fakhretdinova, Azaliia M. Tuliakova, Iulia A. Rusakova, Jost B. Jonas
{"title":"心房颤动和扑动与眼部疾病。乌拉尔眼科和医学研究以及乌拉尔非常古老的研究。","authors":"Mukharram M. Bikbov, Gyulli M. Kazakbaeva, Ellina M. Rakhimova, Songhomitra Panda-Jonas, Albina A. Fakhretdinova, Azaliia M. Tuliakova, Iulia A. Rusakova, Jost B. Jonas","doi":"10.1111/aos.16726","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Purpose</h3>\n \n <p>To assess associations between atrial fibrillation/atrial flutter (AF) and ocular parameters and diseases.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>The population-based Ural Eye and Medical Study (UEMS) and the Ural Very Old Study (UVOS) included 4894 individuals (age: 40+ years) and 835 individuals (age: 85+ years), respectively.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>In the UEMS, AF prevalence (80/4894; 1.6%; 95% CI: 1.3, 2.0) increased from 1/1029 (0.1%) in the age group of 40 to <50 years to 29/619 (4.7%) and 12/159 (7.5%) in the age groups of 70 to <80 years and 80+ years, respectively. Higher AF prevalence correlated with older age (OR: 1.08; 95% CI: 1.04, 1.12; <i>p</i> < 0.001), urban region of habitation (OR: 1.08; 95% CI: 1.04, 1.12; <i>p</i> < 0.001), higher prevalence of cardiovascular disease/stroke (OR: 2.50; 95% CI: 1.32, 4.72; <i>p</i> < 0.001) and lower prevalence of neck pain (OR: 0.35; 95% CI: 0.14, 0.85; <i>p</i> = 0.02), higher serum concentration of bilirubin (OR: 1.03; 95% CI: 1.02, 1.05; <i>p</i> < 0.001) and lower prothrombin index (OR: 0.96; 95% CI: 0.93, 0.99; <i>p</i> = 0.003), higher stage of arterial hypertension (OR: 1.52; 95% CI: 1.01, 2.28; <i>p</i> = 0.04) and higher ankle-brachial index (OR: 22.1; 95% CI: 4.45, 1.10; <i>p</i> < 0.001). In that model, AF prevalence was not associated with ocular parameters such as intraocular pressure (<i>p</i> = 0.52), retinal nerve fibre layer thickness (<i>p</i> = 0.70), refractive error (<i>p</i> = 0.13), axial length (<i>p</i> = 0.14), nuclear cataract degree (<i>p</i> = 0.50) and prevalence (<i>p</i> = 0.40), cortical cataract degree (<i>p</i> = 0.43) and presence (<i>p</i> = 0.17), lens pseudoexfoliation (<i>p</i> = 0.58), status after cataract surgery (<i>p</i> = 0.38), age-related macular degeneration prevalence (<i>p</i> = 0.63), open-angle glaucoma presence (<i>p</i> = 0.90) and stage (<i>p</i> = 0.55), angle-closure glaucoma prevalence (<i>p</i> = 0.99) and stage (<i>p</i> = 0.99), diabetic retinopathy prevalence presence (<i>p</i> = 0.37) and stage (<i>p</i> = 0.32), and myopic macular degeneration (<i>p</i> = 0.98). In the UVOS, similar results were obtained.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>In these multi-ethnic populations from Russia, AF prevalence was not associated with any major ocular disease and may not play a major role in the pathogenesis of these disorders.</p>\n </section>\n </div>","PeriodicalId":6915,"journal":{"name":"Acta Ophthalmologica","volume":"102 7","pages":"e1057-e1065"},"PeriodicalIF":3.0000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Atrial fibrillation and flutter and ocular diseases. The Ural eye and medical study and the Ural very old study\",\"authors\":\"Mukharram M. Bikbov, Gyulli M. Kazakbaeva, Ellina M. Rakhimova, Songhomitra Panda-Jonas, Albina A. Fakhretdinova, Azaliia M. Tuliakova, Iulia A. Rusakova, Jost B. Jonas\",\"doi\":\"10.1111/aos.16726\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Purpose</h3>\\n \\n <p>To assess associations between atrial fibrillation/atrial flutter (AF) and ocular parameters and diseases.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>The population-based Ural Eye and Medical Study (UEMS) and the Ural Very Old Study (UVOS) included 4894 individuals (age: 40+ years) and 835 individuals (age: 85+ years), respectively.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>In the UEMS, AF prevalence (80/4894; 1.6%; 95% CI: 1.3, 2.0) increased from 1/1029 (0.1%) in the age group of 40 to <50 years to 29/619 (4.7%) and 12/159 (7.5%) in the age groups of 70 to <80 years and 80+ years, respectively. Higher AF prevalence correlated with older age (OR: 1.08; 95% CI: 1.04, 1.12; <i>p</i> < 0.001), urban region of habitation (OR: 1.08; 95% CI: 1.04, 1.12; <i>p</i> < 0.001), higher prevalence of cardiovascular disease/stroke (OR: 2.50; 95% CI: 1.32, 4.72; <i>p</i> < 0.001) and lower prevalence of neck pain (OR: 0.35; 95% CI: 0.14, 0.85; <i>p</i> = 0.02), higher serum concentration of bilirubin (OR: 1.03; 95% CI: 1.02, 1.05; <i>p</i> < 0.001) and lower prothrombin index (OR: 0.96; 95% CI: 0.93, 0.99; <i>p</i> = 0.003), higher stage of arterial hypertension (OR: 1.52; 95% CI: 1.01, 2.28; <i>p</i> = 0.04) and higher ankle-brachial index (OR: 22.1; 95% CI: 4.45, 1.10; <i>p</i> < 0.001). In that model, AF prevalence was not associated with ocular parameters such as intraocular pressure (<i>p</i> = 0.52), retinal nerve fibre layer thickness (<i>p</i> = 0.70), refractive error (<i>p</i> = 0.13), axial length (<i>p</i> = 0.14), nuclear cataract degree (<i>p</i> = 0.50) and prevalence (<i>p</i> = 0.40), cortical cataract degree (<i>p</i> = 0.43) and presence (<i>p</i> = 0.17), lens pseudoexfoliation (<i>p</i> = 0.58), status after cataract surgery (<i>p</i> = 0.38), age-related macular degeneration prevalence (<i>p</i> = 0.63), open-angle glaucoma presence (<i>p</i> = 0.90) and stage (<i>p</i> = 0.55), angle-closure glaucoma prevalence (<i>p</i> = 0.99) and stage (<i>p</i> = 0.99), diabetic retinopathy prevalence presence (<i>p</i> = 0.37) and stage (<i>p</i> = 0.32), and myopic macular degeneration (<i>p</i> = 0.98). In the UVOS, similar results were obtained.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>In these multi-ethnic populations from Russia, AF prevalence was not associated with any major ocular disease and may not play a major role in the pathogenesis of these disorders.</p>\\n </section>\\n </div>\",\"PeriodicalId\":6915,\"journal\":{\"name\":\"Acta Ophthalmologica\",\"volume\":\"102 7\",\"pages\":\"e1057-e1065\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Ophthalmologica\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/aos.16726\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Ophthalmologica","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/aos.16726","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Atrial fibrillation and flutter and ocular diseases. The Ural eye and medical study and the Ural very old study
Purpose
To assess associations between atrial fibrillation/atrial flutter (AF) and ocular parameters and diseases.
Methods
The population-based Ural Eye and Medical Study (UEMS) and the Ural Very Old Study (UVOS) included 4894 individuals (age: 40+ years) and 835 individuals (age: 85+ years), respectively.
Results
In the UEMS, AF prevalence (80/4894; 1.6%; 95% CI: 1.3, 2.0) increased from 1/1029 (0.1%) in the age group of 40 to <50 years to 29/619 (4.7%) and 12/159 (7.5%) in the age groups of 70 to <80 years and 80+ years, respectively. Higher AF prevalence correlated with older age (OR: 1.08; 95% CI: 1.04, 1.12; p < 0.001), urban region of habitation (OR: 1.08; 95% CI: 1.04, 1.12; p < 0.001), higher prevalence of cardiovascular disease/stroke (OR: 2.50; 95% CI: 1.32, 4.72; p < 0.001) and lower prevalence of neck pain (OR: 0.35; 95% CI: 0.14, 0.85; p = 0.02), higher serum concentration of bilirubin (OR: 1.03; 95% CI: 1.02, 1.05; p < 0.001) and lower prothrombin index (OR: 0.96; 95% CI: 0.93, 0.99; p = 0.003), higher stage of arterial hypertension (OR: 1.52; 95% CI: 1.01, 2.28; p = 0.04) and higher ankle-brachial index (OR: 22.1; 95% CI: 4.45, 1.10; p < 0.001). In that model, AF prevalence was not associated with ocular parameters such as intraocular pressure (p = 0.52), retinal nerve fibre layer thickness (p = 0.70), refractive error (p = 0.13), axial length (p = 0.14), nuclear cataract degree (p = 0.50) and prevalence (p = 0.40), cortical cataract degree (p = 0.43) and presence (p = 0.17), lens pseudoexfoliation (p = 0.58), status after cataract surgery (p = 0.38), age-related macular degeneration prevalence (p = 0.63), open-angle glaucoma presence (p = 0.90) and stage (p = 0.55), angle-closure glaucoma prevalence (p = 0.99) and stage (p = 0.99), diabetic retinopathy prevalence presence (p = 0.37) and stage (p = 0.32), and myopic macular degeneration (p = 0.98). In the UVOS, similar results were obtained.
Conclusions
In these multi-ethnic populations from Russia, AF prevalence was not associated with any major ocular disease and may not play a major role in the pathogenesis of these disorders.
期刊介绍：
Acta Ophthalmologica is published on behalf of the Acta Ophthalmologica Scandinavica Foundation and is the official scientific publication of the following societies: The Danish Ophthalmological Society, The Finnish Ophthalmological Society, The Icelandic Ophthalmological Society, The Norwegian Ophthalmological Society and The Swedish Ophthalmological Society, and also the European Association for Vision and Eye Research (EVER).
Acta Ophthalmologica publishes clinical and experimental original articles, reviews, editorials, educational photo essays (Diagnosis and Therapy in Ophthalmology), case reports and case series, letters to the editor and doctoral theses.
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