CH-VAD 和 HeartMate III 磁悬浮离心血泵中的湍流场:二次流及其对泵性能的影响。

IF 3 3区 医学 Q2 BIOPHYSICS
Peng Wu, Ke-Jia Zhang, Wen-Jing Xiang, Guan-Ting Du
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引用次数: 0

摘要

二次流道是离心血泵设计中的关键环节之一。间隙小会增加应力水平和血液损伤,而间隙大则可改善血液冲洗并降低应力水平。然而,过大的间隙也会导致强烈的二次流动,造成进一步的血液损伤。磁悬浮血泵依靠磁力实现转子悬浮,因此间隙大小的设计自由度更大。本研究旨在分析 CH-VAD 和 HeartMate III 这两种具有代表性的商用磁悬浮血泵的湍流场和二次流的特征,以及它们对一次流和泵性能的影响。CH-VAD 的次级流道窄而长,导致次级流量低,对主流的干扰小。CH-VAD 的血流损失和血液损伤可能性主要发生在二次流道和叶片间隙处。相比之下,HeartMate III 较宽的间隙对一次流造成了严重干扰,导致入射角大、二次流强和流量损失高。与 CH-VAD 相比,在更高的流速下,入射角更大,造成更大的分离,导致效率显著下降,性能曲线更陡峭。这项研究表明,磁悬浮轴承并不能保证良好的血液兼容性,在设计离心血泵时应更多地关注二次流对泵性能的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Turbulent flow field in maglev centrifugal blood pumps of CH-VAD and HeartMate III: secondary flow and its effects on pump performance

Turbulent flow field in maglev centrifugal blood pumps of CH-VAD and HeartMate III: secondary flow and its effects on pump performance

Secondary flow path is one of the crucial aspects during the design of centrifugal blood pumps. Small clearance size increases stress level and blood damage, while large clearance size can improve blood washout and reduce stress level. Nonetheless, large clearance also leads to strong secondary flows, causing further blood damage. Maglev blood pumps rely on magnetic force to achieve rotor suspension and allow more design freedom of clearance size. This study aims to characterize turbulent flow field and secondary flow as well as its effects on the primary flow and pump performance, in two representative commercial maglev blood pumps of CH-VAD and HeartMate III, which feature distinct designs of secondary flow path. The narrow and long secondary flow path of CH-VAD resulted in low secondary flow rates and low disturbance to the primary flow. The flow loss and blood damage potential of the CH-VAD mainly occurred at the secondary flow path, as well as the blade clearances. By contrast, the wide clearances in HeartMate III induced significant disturbance to the primary flow, resulting in large incidence angle, strong secondary flows and high flow loss. At higher flow rates, the incidence angle was even larger, causing larger separation, leading to a significant decrease of efficiency and steeper performance curve compared with CH-VAD. This study shows that maglev bearings do not guarantee good blood compatibility, and more attention should be paid to the influence of secondary flows on pump performance when designing centrifugal blood pumps.

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来源期刊
Biomechanics and Modeling in Mechanobiology
Biomechanics and Modeling in Mechanobiology 工程技术-工程:生物医学
CiteScore
7.10
自引率
8.60%
发文量
119
审稿时长
6 months
期刊介绍: Mechanics regulates biological processes at the molecular, cellular, tissue, organ, and organism levels. A goal of this journal is to promote basic and applied research that integrates the expanding knowledge-bases in the allied fields of biomechanics and mechanobiology. Approaches may be experimental, theoretical, or computational; they may address phenomena at the nano, micro, or macrolevels. Of particular interest are investigations that (1) quantify the mechanical environment in which cells and matrix function in health, disease, or injury, (2) identify and quantify mechanosensitive responses and their mechanisms, (3) detail inter-relations between mechanics and biological processes such as growth, remodeling, adaptation, and repair, and (4) report discoveries that advance therapeutic and diagnostic procedures. Especially encouraged are analytical and computational models based on solid mechanics, fluid mechanics, or thermomechanics, and their interactions; also encouraged are reports of new experimental methods that expand measurement capabilities and new mathematical methods that facilitate analysis.
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