{"title":"基于廷德尔效应散射和荧光相结合的CDs-MnO2 NS复合材料双信号光学传感平台，用于快速检测抗坏血酸。","authors":"ShuJing Zhou, Jing Wan, Jianmei Zou, Yulan Zhang, Huijun He, Wei Li, Jiale Hu, Jinfang Nie, Yali Yuan and Yun Zhang","doi":"10.1039/D4RA02340D","DOIUrl":null,"url":null,"abstract":"<p >A dual-signal optical sensing platform was successfully developed for the determination of ascorbic acid (AA) based on blue fluorescent carbon dots (CDs) and manganese dioxide nanosheets (MnO<small><sub>2</sub></small> NSs) with strong Tyndall effect (TE) scattering and fluorescence quenching capabilities. In this nanosystem, CDs–MnO<small><sub>2</sub></small> NS composites were employed as probes to evaluate the AA concentration. Owing to the strong reduction, the presence of the target AA could reduce the MnO<small><sub>2</sub></small> NSs to Mn<small><sup>2+</sup></small> and induce the degradation of the MnO<small><sub>2</sub></small> NSs, resulting in a significant decrease in the TE scattering intensity of the MnO<small><sub>2</sub></small> NSs and the fluorescence recovery of the CDs. Therefore, a novel optical sensor based on TE scattering and fluorescence dual detectors was developed for the sensitive determination of AA. Under optimized conditions, the limits of detection (LODs) of the two modes were 113 and 3 nM, respectively. Furthermore, the dual-signal optical sensing platform was successfully applied for the detection of AA in human serum.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 25","pages":" 17491-17497"},"PeriodicalIF":4.6000,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137496/pdf/","citationCount":"0","resultStr":"{\"title\":\"A dual-signal optical sensing platform of CDs–MnO2 NS composites for facile detection of ascorbic acid based on a combination of Tyndall effect scattering and fluorescence†\",\"authors\":\"ShuJing Zhou, Jing Wan, Jianmei Zou, Yulan Zhang, Huijun He, Wei Li, Jiale Hu, Jinfang Nie, Yali Yuan and Yun Zhang\",\"doi\":\"10.1039/D4RA02340D\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >A dual-signal optical sensing platform was successfully developed for the determination of ascorbic acid (AA) based on blue fluorescent carbon dots (CDs) and manganese dioxide nanosheets (MnO<small><sub>2</sub></small> NSs) with strong Tyndall effect (TE) scattering and fluorescence quenching capabilities. In this nanosystem, CDs–MnO<small><sub>2</sub></small> NS composites were employed as probes to evaluate the AA concentration. Owing to the strong reduction, the presence of the target AA could reduce the MnO<small><sub>2</sub></small> NSs to Mn<small><sup>2+</sup></small> and induce the degradation of the MnO<small><sub>2</sub></small> NSs, resulting in a significant decrease in the TE scattering intensity of the MnO<small><sub>2</sub></small> NSs and the fluorescence recovery of the CDs. Therefore, a novel optical sensor based on TE scattering and fluorescence dual detectors was developed for the sensitive determination of AA. Under optimized conditions, the limits of detection (LODs) of the two modes were 113 and 3 nM, respectively. Furthermore, the dual-signal optical sensing platform was successfully applied for the detection of AA in human serum.</p>\",\"PeriodicalId\":102,\"journal\":{\"name\":\"RSC Advances\",\"volume\":\" 25\",\"pages\":\" 17491-17497\"},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137496/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"RSC Advances\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://pubs.rsc.org/en/content/articlelanding/2024/ra/d4ra02340d\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"RSC Advances","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/ra/d4ra02340d","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
基于蓝色荧光碳点（CD）和具有强廷德尔效应（TE）散射和荧光淬灭能力的二氧化锰纳米片（MnO2 NSs），成功开发了一种测定抗坏血酸（AA）的双信号光学传感平台。在这一纳米系统中，CDs-MnO2 NS 复合物被用作评估 AA 浓度的探针。由于强还原性，目标 AA 的存在可将 MnO2 NSs 还原成 Mn2+，并诱导 MnO2 NSs 降解，从而导致 MnO2 NSs 的 TE 散射强度和 CD 的荧光恢复能力显著下降。因此，我们开发了一种基于 TE 散射和荧光双检测器的新型光学传感器，用于灵敏测定 AA。在优化条件下，两种模式的检测限分别为 113 nM 和 3 nM。此外，该双信号光学传感平台还被成功应用于人血清中 AA 的检测。
A dual-signal optical sensing platform of CDs–MnO2 NS composites for facile detection of ascorbic acid based on a combination of Tyndall effect scattering and fluorescence†
A dual-signal optical sensing platform was successfully developed for the determination of ascorbic acid (AA) based on blue fluorescent carbon dots (CDs) and manganese dioxide nanosheets (MnO2 NSs) with strong Tyndall effect (TE) scattering and fluorescence quenching capabilities. In this nanosystem, CDs–MnO2 NS composites were employed as probes to evaluate the AA concentration. Owing to the strong reduction, the presence of the target AA could reduce the MnO2 NSs to Mn2+ and induce the degradation of the MnO2 NSs, resulting in a significant decrease in the TE scattering intensity of the MnO2 NSs and the fluorescence recovery of the CDs. Therefore, a novel optical sensor based on TE scattering and fluorescence dual detectors was developed for the sensitive determination of AA. Under optimized conditions, the limits of detection (LODs) of the two modes were 113 and 3 nM, respectively. Furthermore, the dual-signal optical sensing platform was successfully applied for the detection of AA in human serum.
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