"最公平的药物"：将康复血浆作为治疗 SARS-CoV-2 的临床研究如何为大流行后公共部门的药物开发方法提供有用信息。

IF 1.6 4区哲学 Q2 ETHICS

Journal of Law Medicine & Ethics Pub Date : 2024-01-01 Epub Date: 2024-05-31 DOI:10.1017/jme.2024.51

Quinn Grundy, Chantal Campbell, Ridwaanah Ali, Matthew Herder, Kelly Holloway

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引用次数: 0

摘要

治疗 COVID-19 的康复血浆干预性临床研究主要由公共部门（包括血液服务运营商）资助和主导。我们旨在分析疗养血浆临床研究的过程，以了解制药业生物制药研发的替代方案，尤其是在公共部门扮演主导角色的情况下。我们对 2020-2021 年期间有目的性地抽取的具有重要影响的疗养血浆临床研究进行了定性、批判性案例研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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"A Most Equitable Drug": How the Clinical Studies of Convalescent Plasma as a Treatment for SARS-CoV-2 Might Usefully Inform Post-Pandemic Public Sector Approaches to Drug Development.

Interventional clinical studies of convalescent plasma to treat COVID-19 were predominantly funded and led by public sector actors, including blood services operators. We aimed to analyze the processes of clinical studies of convalescent plasma to understand alternatives to pharmaceutical industry biopharmaceutical research and development, particularly where public sector actors play a dominant role. We conducted a qualitative, critical case study of purposively sampled prominent and impactful clinical studies of convalescent plasma during 2020-2021.

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来源期刊

Journal of Law Medicine & Ethics 医学-医学：法

CiteScore

2.90

自引率

4.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Material published in The Journal of Law, Medicine & Ethics (JLME) contributes to the educational mission of The American Society of Law, Medicine & Ethics, covering public health, health disparities, patient safety and quality of care, and biomedical science and research. It provides articles on such timely topics as health care quality and access, managed care, pain relief, genetics, child/maternal health, reproductive health, informed consent, assisted dying, ethics committees, HIV/AIDS, and public health. Symposium issues review significant policy developments, health law court decisions, and books.