提高结构生物学研究的复杂性

IF 12.5 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
Eva Nogales
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引用次数: 0

摘要

大分子参与了无数调节细胞功能的相互作用。虽然多年来结构生物学的进步是通过降低这种复杂性取得的,但要从分子角度了解生物过程,就必须对更大和更动态的分子组装进行表征。冷冻电镜技术正在迎接这一挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Building up complexity in structural biology studies
Macromolecules are involved in myriads of interactions that regulate their cellular function. While years of structural biology progress was built by reducing this complexity, a molecular understanding of biological processes requires the characterization of ever larger and more dynamic molecular assemblies. Cryo-electron microscopy is rising to this challenge.
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来源期刊
Nature Structural & Molecular Biology
Nature Structural & Molecular Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOPHYSICS
CiteScore
22.00
自引率
1.80%
发文量
160
审稿时长
3-8 weeks
期刊介绍: Nature Structural & Molecular Biology is a comprehensive platform that combines structural and molecular research. Our journal focuses on exploring the functional and mechanistic aspects of biological processes, emphasizing how molecular components collaborate to achieve a particular function. While structural data can shed light on these insights, our publication does not require them as a prerequisite.
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