Arcenio A Lendo-López, José E Galván-García, Anival Trujillo-García, Luis F Aguilar-Aguilar, Jorge A Garay-Hansen, Omar Ramírez-Lastra, Óscar Zapana-Céspedes, Bernardo Meléndez-Mendoza, Ramiro J Fajardo-Losada, Salvador I Sandoval-Hernández, Alan A León-Bojorquez, Luis A González-Serrato, Kevin A Zurroza-Luna, Juan M Palacios-Rodríguez
{"title":"[对急性 ST 段抬高型心肌梗死患者使用机械溶栓疗法与仅使用 IIB/IIIA 糖蛋白抑制剂相比,院内重大心脏事件的发生率]。","authors":"Arcenio A Lendo-López, José E Galván-García, Anival Trujillo-García, Luis F Aguilar-Aguilar, Jorge A Garay-Hansen, Omar Ramírez-Lastra, Óscar Zapana-Céspedes, Bernardo Meléndez-Mendoza, Ramiro J Fajardo-Losada, Salvador I Sandoval-Hernández, Alan A León-Bojorquez, Luis A González-Serrato, Kevin A Zurroza-Luna, Juan M Palacios-Rodríguez","doi":"10.24875/ACM.23000228","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To identify the incidence of in-hospital major adverse cardiac events (MACE) with the use of mechanic thromboaspiration plus IIb/IIIa glycoprotein inhibitors versus only use of IIb/IIIa glycoprotein inhibitors on patients with acute ST elevation myocardial infarction.</p><p><strong>Method: </strong>Retrospective, observational, cohort analytic study, on patients with acute ST elevation myocardial infarction that had angiography thrombus TIMI 5 grade, treated between October 2021 and December 2022.</p><p><strong>Results: </strong>A total of 237 patients were included. In 113 patients thromboaspiration were used, 124 patients didn't used. 81.6% were men. In-hospital MACE occurred on 31.9% of patients with thromboaspiration use vs. 30.6% on patients with no use (RR: 1.05; IC95%: 0.61-1.93; p = 0.840). Incidence of malignant arrhythmias were of 8% with thromboaspiration use vs. 1.6% on patients with no use (RR: 5.27; IC95%: 1.11-24.97; p = 0.020).</p><p><strong>Conclusions: </strong>The use of thromboaspiration on concomitant treatment with IIb/IIIa glycoprotein inhibitors was similar with only IIb/IIIa glycoprotein inhibitors in reducing incidence of in-hospital MACE on patients with ST elevation acute myocardial infarction and high thrombus burden. The study has several limitations, so results should be taken with caution.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"467-473"},"PeriodicalIF":0.0000,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Incidence of intrahospitalary major cardiac events with the use of mechanic thromboaspiration versus only use of IIB/IIIA glucoprotein inhibitors on patients with acute ST elevation myocardial infarction].\",\"authors\":\"Arcenio A Lendo-López, José E Galván-García, Anival Trujillo-García, Luis F Aguilar-Aguilar, Jorge A Garay-Hansen, Omar Ramírez-Lastra, Óscar Zapana-Céspedes, Bernardo Meléndez-Mendoza, Ramiro J Fajardo-Losada, Salvador I Sandoval-Hernández, Alan A León-Bojorquez, Luis A González-Serrato, Kevin A Zurroza-Luna, Juan M Palacios-Rodríguez\",\"doi\":\"10.24875/ACM.23000228\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To identify the incidence of in-hospital major adverse cardiac events (MACE) with the use of mechanic thromboaspiration plus IIb/IIIa glycoprotein inhibitors versus only use of IIb/IIIa glycoprotein inhibitors on patients with acute ST elevation myocardial infarction.</p><p><strong>Method: </strong>Retrospective, observational, cohort analytic study, on patients with acute ST elevation myocardial infarction that had angiography thrombus TIMI 5 grade, treated between October 2021 and December 2022.</p><p><strong>Results: </strong>A total of 237 patients were included. In 113 patients thromboaspiration were used, 124 patients didn't used. 81.6% were men. In-hospital MACE occurred on 31.9% of patients with thromboaspiration use vs. 30.6% on patients with no use (RR: 1.05; IC95%: 0.61-1.93; p = 0.840). Incidence of malignant arrhythmias were of 8% with thromboaspiration use vs. 1.6% on patients with no use (RR: 5.27; IC95%: 1.11-24.97; p = 0.020).</p><p><strong>Conclusions: </strong>The use of thromboaspiration on concomitant treatment with IIb/IIIa glycoprotein inhibitors was similar with only IIb/IIIa glycoprotein inhibitors in reducing incidence of in-hospital MACE on patients with ST elevation acute myocardial infarction and high thrombus burden. The study has several limitations, so results should be taken with caution.</p>\",\"PeriodicalId\":93885,\"journal\":{\"name\":\"Archivos de cardiologia de Mexico\",\"volume\":\" \",\"pages\":\"467-473\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archivos de cardiologia de Mexico\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24875/ACM.23000228\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivos de cardiologia de Mexico","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24875/ACM.23000228","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Incidence of intrahospitalary major cardiac events with the use of mechanic thromboaspiration versus only use of IIB/IIIA glucoprotein inhibitors on patients with acute ST elevation myocardial infarction].
Objective: To identify the incidence of in-hospital major adverse cardiac events (MACE) with the use of mechanic thromboaspiration plus IIb/IIIa glycoprotein inhibitors versus only use of IIb/IIIa glycoprotein inhibitors on patients with acute ST elevation myocardial infarction.
Method: Retrospective, observational, cohort analytic study, on patients with acute ST elevation myocardial infarction that had angiography thrombus TIMI 5 grade, treated between October 2021 and December 2022.
Results: A total of 237 patients were included. In 113 patients thromboaspiration were used, 124 patients didn't used. 81.6% were men. In-hospital MACE occurred on 31.9% of patients with thromboaspiration use vs. 30.6% on patients with no use (RR: 1.05; IC95%: 0.61-1.93; p = 0.840). Incidence of malignant arrhythmias were of 8% with thromboaspiration use vs. 1.6% on patients with no use (RR: 5.27; IC95%: 1.11-24.97; p = 0.020).
Conclusions: The use of thromboaspiration on concomitant treatment with IIb/IIIa glycoprotein inhibitors was similar with only IIb/IIIa glycoprotein inhibitors in reducing incidence of in-hospital MACE on patients with ST elevation acute myocardial infarction and high thrombus burden. The study has several limitations, so results should be taken with caution.