卵巢早衰发病机制中的心理压力因素及潜在干预措施。

IF 2 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM
Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-05-30 DOI:10.1080/09513590.2024.2360085
Ying-Pei Xu, Ji-Chun Fu, Zhi-Lin Hong, De-Fei Zeng, Chao-Qin Guo, Ping Li, Jin-Xiang Wu
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引用次数: 0

摘要

早发性卵巢功能不全(POI)是一种常见的妇科内分泌疾病,严重影响妇女的身心健康和生育能力,其发病率呈逐年上升趋势。随着社会经济和科技的发展,社会、生活和环境因素导致的焦虑、抑郁等心理压力可能是POI的危险因素之一。我们利用PubMed检索了过去10年发表的经同行评审的英文原版手稿,以确定有关各种压力与卵巢功能下降之间关系的既有研究和实验研究。应激相关因素导致的氧化应激、卵泡闭锁和卵母细胞过度活化可能是卵巢功能损伤的主要原因。本文综述了心理应激因素与卵巢功能减退之间的关系以及可能的早期干预措施,以期为今后的临床治疗和干预提供新思路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Psychological stressors involved in the pathogenesis of premature ovarian insufficiency and potential intervention measures.

Premature ovarian insufficiency (POI) is a common gynecological endocrine disease, which seriously affects women's physical and mental health and fertility, and its incidence is increasing year by year. With the development of social economy and technology, psychological stressors such as anxiety and depression caused by social, life and environmental factors may be one of the risk factors for POI. We used PubMed to search peer-reviewed original English manuscripts published over the last 10 years to identify established and experimental studies on the relationship between various types of stress and decreased ovarian function. Oxidative stress, follicular atresia, and excessive activation of oocytes, caused by Stress-associated factors may be the main causes of ovarian function damage. This article reviews the relationship between psychological stressors and hypoovarian function and the possible early intervention measures in order to provide new ideas for future clinical treatment and intervention.

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来源期刊
Gynecological Endocrinology
Gynecological Endocrinology 医学-妇产科学
CiteScore
4.40
自引率
5.00%
发文量
137
审稿时长
3-6 weeks
期刊介绍: Gynecological Endocrinology , the official journal of the International Society of Gynecological Endocrinology, covers all the experimental, clinical and therapeutic aspects of this ever more important discipline. It includes, amongst others, papers relating to the control and function of the different endocrine glands in females, the effects of reproductive events on the endocrine system, and the consequences of endocrine disorders on reproduction
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