N. Ayyanar, Gracia Nirmala Rani, K. Dharshini, G. Madhumita, N. R. Ramanujam, G. Prabhakar, S. Rajaram
{"title":"基于 GST 的表面等离子体共振可重构生物传感器用于检测人类精子","authors":"N. Ayyanar, Gracia Nirmala Rani, K. Dharshini, G. Madhumita, N. R. Ramanujam, G. Prabhakar, S. Rajaram","doi":"10.1007/s11468-024-02361-x","DOIUrl":null,"url":null,"abstract":"<p>In this paper, we propose a tunable surface plasmon resonance (SPR) biosensor using a phase change chalcogenide material (Ge<sub>2</sub>Sb<sub>2</sub>Te<sub>5</sub>) by the transfer matrix method for the detection of human sperm samples. The growing challenge in natural reproduction lies in the heightened infertility of human sperm, attributed to fluctuations in environmental factors. Effectively tackling these concerning aspects requires the utilization of advanced computer-aided devices. However, the precision of such devices, particularly when dealing with low concentrations of sperm, is not meeting the required standards. The proposed SPR biosensor comprises layers of Ag, BaTiO<sub>3</sub>, and GST for sperm detection. Achieving tunable and improved refractive index sensing along with a substantial figure of merit (FOM) is accomplished by transitioning the structural phase of GST from amorphous to crystalline. The sensing performances are assessed based on sensitivity, quality factor, detection accuracy, and FOM at a wavelength of 633 nm. The average angular sensitivity achieved is 236 deg/RIU for the crystalline phase and 286 deg/RIU for the amorphous phase, respectively. This sensitivity is observed within the dynamic range of refractive index (RI) spanning from 1.33 to 1.3461 RIU. The performance of our proposed SPR biosensor surpasses that of other reported works.</p>","PeriodicalId":736,"journal":{"name":"Plasmonics","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"GST-Based Surface Plasmon Resonance Reconfigurable Biosensor for Detection of Human Sperm\",\"authors\":\"N. Ayyanar, Gracia Nirmala Rani, K. Dharshini, G. Madhumita, N. R. Ramanujam, G. Prabhakar, S. Rajaram\",\"doi\":\"10.1007/s11468-024-02361-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>In this paper, we propose a tunable surface plasmon resonance (SPR) biosensor using a phase change chalcogenide material (Ge<sub>2</sub>Sb<sub>2</sub>Te<sub>5</sub>) by the transfer matrix method for the detection of human sperm samples. The growing challenge in natural reproduction lies in the heightened infertility of human sperm, attributed to fluctuations in environmental factors. Effectively tackling these concerning aspects requires the utilization of advanced computer-aided devices. However, the precision of such devices, particularly when dealing with low concentrations of sperm, is not meeting the required standards. The proposed SPR biosensor comprises layers of Ag, BaTiO<sub>3</sub>, and GST for sperm detection. Achieving tunable and improved refractive index sensing along with a substantial figure of merit (FOM) is accomplished by transitioning the structural phase of GST from amorphous to crystalline. The sensing performances are assessed based on sensitivity, quality factor, detection accuracy, and FOM at a wavelength of 633 nm. The average angular sensitivity achieved is 236 deg/RIU for the crystalline phase and 286 deg/RIU for the amorphous phase, respectively. This sensitivity is observed within the dynamic range of refractive index (RI) spanning from 1.33 to 1.3461 RIU. The performance of our proposed SPR biosensor surpasses that of other reported works.</p>\",\"PeriodicalId\":736,\"journal\":{\"name\":\"Plasmonics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2024-05-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Plasmonics\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://doi.org/10.1007/s11468-024-02361-x\",\"RegionNum\":4,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasmonics","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1007/s11468-024-02361-x","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
GST-Based Surface Plasmon Resonance Reconfigurable Biosensor for Detection of Human Sperm
In this paper, we propose a tunable surface plasmon resonance (SPR) biosensor using a phase change chalcogenide material (Ge2Sb2Te5) by the transfer matrix method for the detection of human sperm samples. The growing challenge in natural reproduction lies in the heightened infertility of human sperm, attributed to fluctuations in environmental factors. Effectively tackling these concerning aspects requires the utilization of advanced computer-aided devices. However, the precision of such devices, particularly when dealing with low concentrations of sperm, is not meeting the required standards. The proposed SPR biosensor comprises layers of Ag, BaTiO3, and GST for sperm detection. Achieving tunable and improved refractive index sensing along with a substantial figure of merit (FOM) is accomplished by transitioning the structural phase of GST from amorphous to crystalline. The sensing performances are assessed based on sensitivity, quality factor, detection accuracy, and FOM at a wavelength of 633 nm. The average angular sensitivity achieved is 236 deg/RIU for the crystalline phase and 286 deg/RIU for the amorphous phase, respectively. This sensitivity is observed within the dynamic range of refractive index (RI) spanning from 1.33 to 1.3461 RIU. The performance of our proposed SPR biosensor surpasses that of other reported works.
期刊介绍:
Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons.
Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.