柔性电子技术在牙科、口腔和颅面医学中的应用

IF 12.3 1区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
Kang-Ning Wang, Zi-Zhan Li, Ze-Min Cai, Lei-Ming Cao, Nian-Nian Zhong, Bing Liu, Kan Zhou, Fang-Yi Huo, Bo Cai, Lin-Lin Bu
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引用次数: 0

摘要

牙齿、口腔和颅面疾病危害健康,降低生活质量。提前获取与疾病相关的信号有利于预防这些疾病的发生或恶化。然而,定期院内检查带来的不便和坚持日常健康监测的困难对个人的依从性提出了挑战,并可能导致有限的预防或治疗。医用柔性电子器件是在柔软、可延伸的基底上制造的适合人体皮肤的电子设备,可对生物物理/生物化学信号进行非侵入式连续监测。它们提供了长期、连续、舒适和无线医疗监测的可能性,并有望通过避免院内检查和治疗来减少时间和经济消耗。因此,用于口腔科早期诊断和疾病监测的柔性电子产品应运而生。值得注意的是,特殊的生物物理/生物化学特性以及牙齿、口腔和颅面区域的环境带来了独特的挑战,柔性电子器件需要巧妙地应对这些挑战,以确保其稳定性、选择性和灵敏度。这篇综述总结了柔性电子器件及其在牙科、口腔和颅面应用中的特殊性,包括监测唾液或龋洞气体相关生物信号、感知面部肌肉/呼吸活动或正畸力产生的机械波动,以及在相关疾病的预防或术后恢复中执行特殊功能。此外,在分析了当前面临的挑战并提出潜在解决方案之后,还提出了 "5I "原则,即不可感知性、智能性、个性化、集成性和不可感知性,以帮助指导柔性电子产品的未来发展,并促进其在牙科、口腔和颅面医学领域的商业化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The applications of flexible electronics in dental, oral, and craniofacial medicine

The applications of flexible electronics in dental, oral, and craniofacial medicine
Dental, oral, and craniofacial diseases jeopardize health and reduce the quality of life. Accessing disease-related signals in advance is beneficial to prevent the occurrence or progression of those diseases. However, the inconvenience of periodical in-hospital examinations and the difficulty of sustaining daily health monitoring challenge personal compliance and possibly lead to limited prevention or treatment. Medical flexible electronics are electric devices fabricated on soft and extensible substrates to fit the human skin and enable non-invasive continuous monitoring of biophysical/biochemical signals. They provide the possibility of long-term, continuous, comfortable, and wireless healthcare monitoring and are expected to alleviate time and economic consumption by avoiding in-hospital examinations and treatment. Therefore, flexible electronics have emerged for early diagnosis and disease monitoring in stomatology. It is noteworthy that special biophysical/biochemical characteristics and the environment of dental, oral, and craniofacial areas bring distinct challenges that flexible electronics need to address ingeniously to ensure their stability, selectivity, and sensitivity. This review summaries flexible electronics and their specificity when used in dental, oral, and craniofacial applications, including monitoring saliva or cavity-gas related biosignals, sensing the mechanical fluctuation from facial muscle/respiratory activities or orthodontic forces, and executing special functions in the prevention or postoperative recovery of relevant diseases. Furthermore, after analyzing current challenges and proposing potential solutions, the “5I” principles of imperceptibility, intelligence, individualization, integration, and inexpensiveness are presented to help guide the future development of flexible electronics and promote their commercialization for dental, oral, and craniofacial medicine.
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来源期刊
CiteScore
17.10
自引率
4.80%
发文量
91
审稿时长
6 weeks
期刊介绍: npj Flexible Electronics is an online-only and open access journal, which publishes high-quality papers related to flexible electronic systems, including plastic electronics and emerging materials, new device design and fabrication technologies, and applications.
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