Elodie Roels, Chiara Debie, Sophie Giraud, Rui Ferreira, Kris Gommeren
{"title":"猫科动物潜在献血者血浆阳性率以及与选定临床变量的关联研究。","authors":"Elodie Roels, Chiara Debie, Sophie Giraud, Rui Ferreira, Kris Gommeren","doi":"10.1111/jvim.17119","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Hemotropic mycoplasmas, hemoplasmas, are epi-erythrocytic parasitic bacteria that can be transmitted through blood transfusion.</p>\n </section>\n \n <section>\n \n <h3> Objectives</h3>\n \n <p>To study the prevalence of hemoplasma infection of potential feline blood donors and investigate the association between <i>Hemoplasma</i> spp. quantitative polymerase chain reaction (qPCR) positivity in blood units and selected variables.</p>\n </section>\n \n <section>\n \n <h3> Animals</h3>\n \n <p>Seven thousand five hundred seventy-three blood units from 4121 privately-owned potential donor cats.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Retrospective observational cross-sectional study. The Banco Sangue Animal (BSA)—Animal Blood Bank medical database was reviewed for all feline donations performed in 2022 in Portugal, Spain, and Belgium. Baseline characteristics and results of blood-borne pathogens screening tests were extracted from the medical records.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Two hundred twelve of 4034 Portuguese donor cats and 2 of 70 Spanish donor cats tested positive for <i>Hemoplasma</i> spp. qPCR in 2022 leading to an overall estimated prevalence of 5.2% (95% CI: 4.5%-5.9%) in potential blood donors. Using multivariable generalized estimation equation models, <i>Hemoplasma</i> spp. qPCR was more often positive among blood units issued from male cats (OR = 1.9, 95% CI: 1.4-2.6, <i>P</i> < .0001), units positive for FeLV (OR = 2.8, 95% CI: 1.4-5.6, <i>P</i> = .0023), and units collected in winter months (OR = 2.5, 95% CI: 1.7-3.6, <i>P</i> < .0001).</p>\n </section>\n \n <section>\n \n <h3> Conclusions and Clinical Importance</h3>\n \n <p>This study underscores the importance of <i>Hemoplasma</i> spp. and other relevant blood-borne pathogens screening at every donation. Implementing stringent screening protocols is crucial to mitigate the risk of hemoplasma transmission via blood transfusions, thereby safeguarding the health and welfare of cats receiving transfusions.</p>\n </section>\n </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":null,"pages":null},"PeriodicalIF":2.1000,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11256158/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prevalence of Hemoplasma spp. positivity in potential feline blood donors and study of the association with selected clinical variables\",\"authors\":\"Elodie Roels, Chiara Debie, Sophie Giraud, Rui Ferreira, Kris Gommeren\",\"doi\":\"10.1111/jvim.17119\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Hemotropic mycoplasmas, hemoplasmas, are epi-erythrocytic parasitic bacteria that can be transmitted through blood transfusion.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>To study the prevalence of hemoplasma infection of potential feline blood donors and investigate the association between <i>Hemoplasma</i> spp. quantitative polymerase chain reaction (qPCR) positivity in blood units and selected variables.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Animals</h3>\\n \\n <p>Seven thousand five hundred seventy-three blood units from 4121 privately-owned potential donor cats.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Retrospective observational cross-sectional study. The Banco Sangue Animal (BSA)—Animal Blood Bank medical database was reviewed for all feline donations performed in 2022 in Portugal, Spain, and Belgium. Baseline characteristics and results of blood-borne pathogens screening tests were extracted from the medical records.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Two hundred twelve of 4034 Portuguese donor cats and 2 of 70 Spanish donor cats tested positive for <i>Hemoplasma</i> spp. qPCR in 2022 leading to an overall estimated prevalence of 5.2% (95% CI: 4.5%-5.9%) in potential blood donors. Using multivariable generalized estimation equation models, <i>Hemoplasma</i> spp. qPCR was more often positive among blood units issued from male cats (OR = 1.9, 95% CI: 1.4-2.6, <i>P</i> < .0001), units positive for FeLV (OR = 2.8, 95% CI: 1.4-5.6, <i>P</i> = .0023), and units collected in winter months (OR = 2.5, 95% CI: 1.7-3.6, <i>P</i> < .0001).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions and Clinical Importance</h3>\\n \\n <p>This study underscores the importance of <i>Hemoplasma</i> spp. and other relevant blood-borne pathogens screening at every donation. Implementing stringent screening protocols is crucial to mitigate the risk of hemoplasma transmission via blood transfusions, thereby safeguarding the health and welfare of cats receiving transfusions.</p>\\n </section>\\n </div>\",\"PeriodicalId\":49958,\"journal\":{\"name\":\"Journal of Veterinary Internal Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-05-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11256158/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Veterinary Internal Medicine\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/jvim.17119\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Internal Medicine","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jvim.17119","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Prevalence of Hemoplasma spp. positivity in potential feline blood donors and study of the association with selected clinical variables
Background
Hemotropic mycoplasmas, hemoplasmas, are epi-erythrocytic parasitic bacteria that can be transmitted through blood transfusion.
Objectives
To study the prevalence of hemoplasma infection of potential feline blood donors and investigate the association between Hemoplasma spp. quantitative polymerase chain reaction (qPCR) positivity in blood units and selected variables.
Animals
Seven thousand five hundred seventy-three blood units from 4121 privately-owned potential donor cats.
Methods
Retrospective observational cross-sectional study. The Banco Sangue Animal (BSA)—Animal Blood Bank medical database was reviewed for all feline donations performed in 2022 in Portugal, Spain, and Belgium. Baseline characteristics and results of blood-borne pathogens screening tests were extracted from the medical records.
Results
Two hundred twelve of 4034 Portuguese donor cats and 2 of 70 Spanish donor cats tested positive for Hemoplasma spp. qPCR in 2022 leading to an overall estimated prevalence of 5.2% (95% CI: 4.5%-5.9%) in potential blood donors. Using multivariable generalized estimation equation models, Hemoplasma spp. qPCR was more often positive among blood units issued from male cats (OR = 1.9, 95% CI: 1.4-2.6, P < .0001), units positive for FeLV (OR = 2.8, 95% CI: 1.4-5.6, P = .0023), and units collected in winter months (OR = 2.5, 95% CI: 1.7-3.6, P < .0001).
Conclusions and Clinical Importance
This study underscores the importance of Hemoplasma spp. and other relevant blood-borne pathogens screening at every donation. Implementing stringent screening protocols is crucial to mitigate the risk of hemoplasma transmission via blood transfusions, thereby safeguarding the health and welfare of cats receiving transfusions.
期刊介绍:
The mission of the Journal of Veterinary Internal Medicine is to advance veterinary medical knowledge and improve the lives of animals by publication of authoritative scientific articles of animal diseases.