{"title":"纳米线设计用于免疫疗法的天真 T 细胞","authors":"Dragana Slavkovic-Lukic, Luca Gattinoni","doi":"10.1038/s41565-024-01651-z","DOIUrl":null,"url":null,"abstract":"Nanowires enable efficient genetic engineering of non-activated naive T cells, providing a technological platform for the generation of gene-modified T cells with maximal therapeutic efficacy.","PeriodicalId":18915,"journal":{"name":"Nature nanotechnology","volume":"19 8","pages":"1085-1086"},"PeriodicalIF":38.1000,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nanowires engineer naive T cells for immunotherapy\",\"authors\":\"Dragana Slavkovic-Lukic, Luca Gattinoni\",\"doi\":\"10.1038/s41565-024-01651-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Nanowires enable efficient genetic engineering of non-activated naive T cells, providing a technological platform for the generation of gene-modified T cells with maximal therapeutic efficacy.\",\"PeriodicalId\":18915,\"journal\":{\"name\":\"Nature nanotechnology\",\"volume\":\"19 8\",\"pages\":\"1085-1086\"},\"PeriodicalIF\":38.1000,\"publicationDate\":\"2024-05-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature nanotechnology\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://www.nature.com/articles/s41565-024-01651-z\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature nanotechnology","FirstCategoryId":"88","ListUrlMain":"https://www.nature.com/articles/s41565-024-01651-z","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
纳米线可对非活化的天真 T 细胞进行高效的基因工程改造,为生成具有最大疗效的基因修饰 T 细胞提供了一个技术平台。
Nanowires engineer naive T cells for immunotherapy
Nanowires enable efficient genetic engineering of non-activated naive T cells, providing a technological platform for the generation of gene-modified T cells with maximal therapeutic efficacy.
期刊介绍:
Nature Nanotechnology is a prestigious journal that publishes high-quality papers in various areas of nanoscience and nanotechnology. The journal focuses on the design, characterization, and production of structures, devices, and systems that manipulate and control materials at atomic, molecular, and macromolecular scales. It encompasses both bottom-up and top-down approaches, as well as their combinations.
Furthermore, Nature Nanotechnology fosters the exchange of ideas among researchers from diverse disciplines such as chemistry, physics, material science, biomedical research, engineering, and more. It promotes collaboration at the forefront of this multidisciplinary field. The journal covers a wide range of topics, from fundamental research in physics, chemistry, and biology, including computational work and simulations, to the development of innovative devices and technologies for various industrial sectors such as information technology, medicine, manufacturing, high-performance materials, energy, and environmental technologies. It includes coverage of organic, inorganic, and hybrid materials.