补充 narasin 或 monensin 以控制自然感染犊牛的球虫病。

IF 1.3 Q3 AGRICULTURE, DAIRY & ANIMAL SCIENCE
Translational Animal Science Pub Date : 2024-04-26 eCollection Date: 2024-01-01 DOI:10.1093/tas/txae069
Tiago Leiva, Reinaldo F Cooke, Pedro V F Lasmar, Rodrigo L Valarelli, José M C De Simas, Dina Maria B Zapa, Luiz Felipe M Couto, Luciana M Heller, Welber D Z Lopes
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引用次数: 0

摘要

本实验比较了 narasin 和 monensin 作为抗球虫药对自然感染艾美耳病菌的犊牛的治疗效果。24 头断奶、未阉割的雄性犊牛(Bos indicus × B. taurus 杂交犊牛)被分配到本实验中(第 -8 天至第 42 天)。根据第 -8 天和第 -7 天收集的粪便样本中的每克卵囊数(OPG)(平均 1,059 ± 101 个卵囊/克),所有犊牛都感染了艾美耳病菌。犊牛饲养在单独的围栏中,每天食用玉米青贮饲料、矿物质混合物和水,此外还食用 200 克/头的谷物补充剂。在第 2 天和第 1 天收集粪便样本检测 OPG,结果平均为初始 OPG 值。根据初始 OPG 值将犊牛分为八个区块,每个区块三头犊牛,每个区块内根据第 1 天记录的体重(BW)进行排序,并分配给接受 narasin(NAR;0.8 毫克/千克体重)、Monensin(MON;1 毫克/千克体重)或无离子诱导剂(CON;阴性对照)的犊牛。离子诱导剂被添加到谷物补充剂中,并在实验的第 0 天至第 42 天提供。第 7、14、21、28、35 和 42 天记录犊牛的体重。在第 6 和 7 天、第 13 和 14 天、第 20 和 21 天、第 26 和 27 天、第 34 和 35 天以及第 41 和 42 天收集粪便样本,进行 OPG 分析,并对连续几天收集的样本结果取平均值。还将来自相同处理和采集日的犊牛的等分粪便样本集中起来,用于确定艾美耳菌的各个种类的流行率。在犊牛体重或生长速度方面,未发现处理效应(P ≥ 0.51)。MON犊牛与NAR犊牛相比,在第7、14和28天检测到处理×天数的交互作用(P P P ≤ 0.03),但在第21、35和42天没有差异(P ≥ 0.48)。如果按所有艾美耳菌属计算,或按牛艾美耳菌和阿拉巴门菌的流行率计算,NAR 和 MON 的抗球虫效力没有差异(P ≥ 0.16)。检测到处理 × 天的交互作用(P = 0.04),对阿拉巴门氏菌的抗球虫效力在处理后更强(P P ≥ 0.40)。总之,42 天的研究结束时,两种离子诱导剂在控制球虫病方面的效果相似,尽管莫能菌素的抗球虫效果在实验早期就已显现。尽管如此,这些结果证实了narasin是一种对自然感染的犊牛有效的抗球虫离子源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Supplementing narasin or monensin to control coccidiosis in naturally infected calves.

This experiment compared narasin and monensin as anticoccidials for calves naturally infected with Eimeria spp. Twenty-four weaned, non-castrated male calves (Bos indicus × B. taurus cross) were assigned to this experiment (days -8 to 42). All calves were infected by Eimeria spp. according to oocyst count per gram (OPG) from fecal samples collected on days -8 and -7 (average 1,059 ± 101 oocysts/g). Calves were housed in individual pens, received corn silage, mineral mix, and water for ad libitum consumption, in addition to a grain-based supplement at 200 g/head daily. Fecal samples were collected on days -2 and -1 for OPG, and results averaged as initial OPG value. Calves were blocked according to initial OPG into eight blocks of three calves each, ranked within each block according to body weight (BW) recorded on day -1, and assigned to receive narasin (NAR; 0.8 mg/kg of BW), monensin (MON; 1 mg/kg of BW), or no ionophore (CON; negative control). Ionophores were added to the grain-based supplement, and offered from days 0 to 42 of the experiment. Calf BW was recorded on days 7, 14, 21, 28, 35, and 42. Fecal samples were collected on days 6 and 7, 13 and 14, 20 and 21, 26 and 27, 34 and 35, and 41 and 42 for OPG analysis, and results from samples collected on consecutive days were averaged. Aliquoted fecal samples were also pooled across calves from the same treatment and collection days, and used to determine the prevalence of individual species of Eimeria. No treatment effects were detected (P ≥ 0.51) for calf BW or growth rate. A treatment × day interaction was detected (P < 0.01) for OPG, as NAR and MON calves had less (P < 0.01) OPG compared with CON calves beginning on day 7. The OPG was also less (P ≤ 0.03) in MON compared with NAR calves on days 7, 14, and 28, but did not differ (P ≥ 0.48) on days 21, 35, and 42. The anticoccidial efficacy of NAR and MON did not differ (P ≥ 0.16) when calculated across all Eimeria spp., or according to prevalence of E. bovis and E. alabamensins. A treatment × day interaction was detected (P = 0.04) for anticoccidial efficacy to E. alabamensis, which was greater (P < 0.01) in MON calves on days 7 and 14 and did not differ (P ≥ 0.40) afterward. Collectively, both ionophores were similarly effective in controlling coccidiosis upon completion of the 42-d study, although the anticoccidial effects of monensin were noted earlier in the experiment. Nonetheless, these results corroborate narasin as an efficient anticoccidial ionophore for naturally infected calves.

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来源期刊
Translational Animal Science
Translational Animal Science Veterinary-Veterinary (all)
CiteScore
2.80
自引率
15.40%
发文量
149
审稿时长
8 weeks
期刊介绍: Translational Animal Science (TAS) is the first open access-open review animal science journal, encompassing a broad scope of research topics in animal science. TAS focuses on translating basic science to innovation, and validation of these innovations by various segments of the allied animal industry. Readers of TAS will typically represent education, industry, and government, including research, teaching, administration, extension, management, quality assurance, product development, and technical services. Those interested in TAS typically include animal breeders, economists, embryologists, engineers, food scientists, geneticists, microbiologists, nutritionists, veterinarians, physiologists, processors, public health professionals, and others with an interest in animal production and applied aspects of animal sciences.
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