{"title":"使用低温保存动脉和自体静脉原位修复 MRSA 菌血症引起的霉菌性胸腹主动脉瘤","authors":"Dar Chung , Eanas Yassa","doi":"10.1016/j.avsurg.2024.100296","DOIUrl":null,"url":null,"abstract":"<div><p>Mycotic aortic aneurysm (MAA) is a rare disease process associated with high morbidity and mortality, especially if left untreated. Currently, there is no consensus on optimal management for MAA but early diagnosis is vital for improving chances of survival. Treatment with antibiotics is recommended followed by surgical repair. We present the unique case of a 33-year-old male who presented with a mycotic thoracoabdominal aneurysm that was treated via open <em>in-situ</em> repair with cryopreserved artery, celiac and superior mesenteric artery bypasses, and ligation of bilateral renal arteries. The patient subsequently underwent a successful kidney transplant several years later and currently remains dialysis free. CT imaging at 1-year and 5-years demonstrated patent bypasses without evidence of re-infection or aneurysmal changes to the cryopreserved arterial graft. This case underscores the myriad of challenges associated with managing MAA, while also presenting the opportunities to surmount these challenges through a personalized and multidisciplinary treatment approach.</p></div>","PeriodicalId":72235,"journal":{"name":"Annals of vascular surgery. Brief reports and innovations","volume":"4 2","pages":"Article 100296"},"PeriodicalIF":0.0000,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772687824000485/pdfft?md5=4e373830d88440077574699d160af513&pid=1-s2.0-S2772687824000485-main.pdf","citationCount":"0","resultStr":"{\"title\":\"In-situ repair of a mycotic thoracoabdominal aortic aneurysm caused by MRSA bacteremia using cryopreserved artery and autogenous vein\",\"authors\":\"Dar Chung , Eanas Yassa\",\"doi\":\"10.1016/j.avsurg.2024.100296\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Mycotic aortic aneurysm (MAA) is a rare disease process associated with high morbidity and mortality, especially if left untreated. Currently, there is no consensus on optimal management for MAA but early diagnosis is vital for improving chances of survival. Treatment with antibiotics is recommended followed by surgical repair. We present the unique case of a 33-year-old male who presented with a mycotic thoracoabdominal aneurysm that was treated via open <em>in-situ</em> repair with cryopreserved artery, celiac and superior mesenteric artery bypasses, and ligation of bilateral renal arteries. The patient subsequently underwent a successful kidney transplant several years later and currently remains dialysis free. CT imaging at 1-year and 5-years demonstrated patent bypasses without evidence of re-infection or aneurysmal changes to the cryopreserved arterial graft. This case underscores the myriad of challenges associated with managing MAA, while also presenting the opportunities to surmount these challenges through a personalized and multidisciplinary treatment approach.</p></div>\",\"PeriodicalId\":72235,\"journal\":{\"name\":\"Annals of vascular surgery. Brief reports and innovations\",\"volume\":\"4 2\",\"pages\":\"Article 100296\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772687824000485/pdfft?md5=4e373830d88440077574699d160af513&pid=1-s2.0-S2772687824000485-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of vascular surgery. Brief reports and innovations\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772687824000485\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of vascular surgery. Brief reports and innovations","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772687824000485","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
霉菌性主动脉瘤(MAA)是一种罕见的疾病,发病率和死亡率都很高,尤其是在未经治疗的情况下。目前,关于 MAA 的最佳治疗方法尚未达成共识,但早期诊断对提高存活率至关重要。建议使用抗生素治疗,然后进行手术修复。我们介绍了一例独特的病例,患者是一名 33 岁的男性,患有霉菌性胸腹腔动脉瘤,通过低温保存动脉、腹腔动脉和肠系膜上动脉旁路以及结扎双侧肾动脉进行原位开放修补术治疗。几年后,患者成功接受了肾移植手术,目前仍未接受透析治疗。1 年和 5 年的 CT 成像显示旁路通畅,低温保存的动脉移植物没有再感染或动脉瘤变化的迹象。该病例强调了治疗 MAA 所面临的无数挑战,同时也提供了通过个性化和多学科治疗方法克服这些挑战的机会。
In-situ repair of a mycotic thoracoabdominal aortic aneurysm caused by MRSA bacteremia using cryopreserved artery and autogenous vein
Mycotic aortic aneurysm (MAA) is a rare disease process associated with high morbidity and mortality, especially if left untreated. Currently, there is no consensus on optimal management for MAA but early diagnosis is vital for improving chances of survival. Treatment with antibiotics is recommended followed by surgical repair. We present the unique case of a 33-year-old male who presented with a mycotic thoracoabdominal aneurysm that was treated via open in-situ repair with cryopreserved artery, celiac and superior mesenteric artery bypasses, and ligation of bilateral renal arteries. The patient subsequently underwent a successful kidney transplant several years later and currently remains dialysis free. CT imaging at 1-year and 5-years demonstrated patent bypasses without evidence of re-infection or aneurysmal changes to the cryopreserved arterial graft. This case underscores the myriad of challenges associated with managing MAA, while also presenting the opportunities to surmount these challenges through a personalized and multidisciplinary treatment approach.